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[伴有角膜累及的结膜上皮内癌的替代性治疗性切除术]

[Alternative therapeutic excision of intraepithelial conjunctival carcinoma with corneal extension].

作者信息

Zemba M, Stamate Alina-Cristina, Avram Corina Ioana, Sîrbu Laura Nicoleta Urucu, Camburu Raluca Lăcrămioara, Ochinciuc Uliana, Burcea M

出版信息

Oftalmologia. 2013;57(4):22-6.

Abstract

Surgical treatment for conjunctival neoplasms, with wide local excision, with or without supplemental cryotherapy to the surgical margins represents the treatment of choice for this pathology. In some cases, these neoplasms can be diffuse or multifocal, with borders that are difficult to detect clinically, such that topical therapies offer a more efficient method for treating the entire ocular surface, delivering high drug concentrations at this level, with negligible systemic side effects. Beginning from the clinical case of a patient diagnosed with conjunctival intraepithelial neoplasia, we try to present other therapeutical alternatives, although in this case the therapeutical approach was the classic one.

摘要

结膜肿瘤的手术治疗,采用广泛局部切除,手术切缘可辅以或不辅以冷冻疗法,是这种病理情况的首选治疗方法。在某些情况下,这些肿瘤可能是弥漫性或多灶性的,其边界在临床上难以检测,因此局部治疗为治疗整个眼表提供了一种更有效的方法,可在此水平提供高药物浓度,且全身副作用可忽略不计。从一名被诊断为结膜上皮内瘤变患者的临床病例开始,我们试图介绍其他治疗选择,尽管在该病例中治疗方法是经典的。

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