Revest M, Patrat-Delon S, Devillers A, Tattevin P, Michelet C
Service des maladies infectieuses et réanimation médicale, CHU de Rennes, 2, rue Henri-Le-Guilloux, 35033 Rennes cedex 9, France; CIC Inserm 0203, université Rennes 1, CHU de Rennes, 2, rue Henri-Le-Guilloux, 35033 Rennes cedex 9, France.
Service des maladies infectieuses et réanimation médicale, CHU de Rennes, 2, rue Henri-Le-Guilloux, 35033 Rennes cedex 9, France.
Med Mal Infect. 2014 Jun;44(6):251-60. doi: 10.1016/j.medmal.2014.04.007. Epub 2014 May 18.
The diagnosis of some infectious diseases is sometimes difficult to make and new diagnostic tools have been regularly assessed to that end. 18fluoro-deoxyglucose ((18)FDG) positron-emission tomography (PET) coupled with computed tomography (CT) is one of these new procedures. It has been evaluated for numerous infectious diseases with uneven results. A literature review allowed drawing some conclusions. First, (18)FDG-PET/CT is not currently a first-line procedure for infectious diseases. Second, it has proved useful for the evaluation of patients presenting with fever of unknown origin (FUO). Its negative predictive value is 100%: the symptoms of patients experiencing FUO with negative first-line investigations and a negative (18)FDG-PET/CT will almost always spontaneously disappear. Third, (18)FDG-PET/CT also seems to be contributive for the diagnosis of vascular prosthesis infections or osteomyelitis. Fourth, it has promising results for patients presenting with infective endocarditis, especially for secondary infectious foci, or for patients presenting with suspected infection of pacemakers or implanted defibrillator; but results are still preliminary and must be confirmed. Finally(18)FDG-PET/CT cannot be recommended yet for other infectious diseases due to lack of published data.
某些传染病的诊断有时很难做出，为此人们一直在定期评估新的诊断工具。18氟脱氧葡萄糖（18FDG）正电子发射断层扫描（PET）与计算机断层扫描（CT）相结合就是其中一种新方法。它已针对多种传染病进行了评估，结果参差不齐。通过文献综述得出了一些结论。首先，18FDG-PET/CT目前并非传染病的一线诊断方法。其次，它已被证明对不明原因发热（FUO）患者的评估有用。其阴性预测值为100%：一线检查结果为阴性且18FDG-PET/CT结果为阴性的FUO患者的症状几乎总会自行消失。第三，18FDG-PET/CT似乎对血管假体感染或骨髓炎的诊断也有帮助。第四，它对感染性心内膜炎患者，尤其是对继发性感染灶患者，或对疑似起搏器或植入式除颤器感染的患者有很有前景的结果；但结果仍属初步，必须得到证实。最后，由于缺乏已发表的数据，18FDG-PET/CT目前还不能推荐用于其他传染病。
