Günther T, Rebentisch E, Vormann J, König M, Ising H
Institut für Molekularbiologie und Biochemie, Freie Universität Berlin, FRG.
Biol Trace Elem Res. 1988 Jun;16(1):43-50. doi: 10.1007/BF02795332.
In rats, Mg deficiency caused a moderate hearing loss, measured by means of evoked potentials at 10 and 20 kHz, which was repaired after refeeding a normal diet. Application of 700 mg/kg salicylic acid or injection of 5 x 100 mg/kg gentamicin also caused a reversible hearing loss in normally fed rats. Treatment of Zn-deficient rats with salicylic acid produced a stronger although reversible hearing loss than in normally fed salicylate-treated rats. Treatment of Mg-deficient rats with gentamicin induced a strong hearing loss that was nearly complete and irreversible in 9 of 25 rats.
在大鼠中，镁缺乏导致中度听力损失，通过10和20千赫兹的诱发电位测量，在重新喂食正常饮食后听力得以恢复。给正常喂食的大鼠应用700毫克/千克水杨酸或注射5×100毫克/千克庆大霉素也会导致可逆性听力损失。用水杨酸治疗缺锌大鼠产生的听力损失比正常喂食且用水杨酸治疗的大鼠更严重，尽管也是可逆的。用庆大霉素治疗缺镁大鼠会导致严重听力损失，25只大鼠中有9只的听力损失几乎完全且不可逆。
