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镉和锌对蚯蚓(陆正蚓)的急性毒性

Acute toxicity of cadmium and zinc in the earthworm (Lumbricus terrestris).

作者信息

Nguyen Q, Furst A

机构信息

Institute of Chemical Biology, University of San Francisco, CA 94117-1080.

出版信息

Biol Trace Elem Res. 1988 Dec;18:81-3. doi: 10.1007/BF02917491.

Abstract

Studies are continuing to explore the use of the earthworm (Lumbricus terrestris) for the determination of the acute toxicity of metal compounds. Worms were injected intraperitoneally with cadmium and zinc chlorides, and also zinc chloride followed by cadmium chloride to see if zinc could protect against the toxicity of cadmium. The 48 h acute toxicity (LD50) values were 22 and 23 mg/kg for Cd and Zn respectively and 30 mg/kg for Cd after the worms were pretreated with Zn. It appears that the earthworm can be a useful test subject for obtaining preliminary information on metal toxicity.

摘要

研究人员正在继续探索利用蚯蚓(陆正蚓)来测定金属化合物的急性毒性。将氯化镉和氯化锌腹腔注射到蚯蚓体内,还先注射氯化锌再注射氯化镉,以观察锌是否能抵御镉的毒性。镉和锌的48小时急性毒性(半数致死剂量)值分别为22毫克/千克和23毫克/千克,在用锌预处理蚯蚓后,镉的半数致死剂量值为30毫克/千克。看来蚯蚓可以成为获取有关金属毒性初步信息的有用测试对象。

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