Los Angeles Center for Women's Health, California Hospital Medical Center, 1513 South Grand Avenue, Suite 400, Los Angeles, California, 90015.
J Surg Oncol. 2014 Jul;110(1):68-74. doi: 10.1002/jso.23620. Epub 2014 May 21.
Intraoperative radiotherapy (IORT) of the breast is the administration of a single fraction of radiation to the tumor bed while shielding low risk and uninvolved tissues from the effects of radiation. The TARGIT A and ELIOT trials demonstrate efficacy of IORT when administered at the time of lumpectomy to post-menopausal women with low to intermediate grade, lymph node negative, invasive ductal carcinoma, consistent with international guidelines defining suitable candidates for accelerated partial breast radiotherapy.
术中放疗（IORT）是在对肿瘤床进行单次放射剂量的同时，对低风险和未受影响的组织进行屏蔽，以避免辐射的影响。TARGIT A 和 ELIOT 试验表明，在对绝经后、淋巴结阴性、低至中等级别、浸润性导管癌的女性行保乳手术后，给予 IORT 是有效的，这符合国际指南中对加速部分乳腺放疗的合适候选者的定义。
