Yoshihara Tomoyuki, Kanazawa Ryuzaburo, Maeshima Shinichiro, Osawa Aiko, Ochiai Ikuo, Uemiya Nahoko, Kohyama Shinya, Yamane Fumitaka, Ishihara Shoichiro
Department of Neurosurgery, Nagareyama Central Hospital, Nagareyama, Japan.
Department of Rehabilitation Medicine II, School of Medicine, Fujita Health University, Toyoake, Japan.
Case Rep Neurol. 2014 Apr 16;6(1):116-21. doi: 10.1159/000362515. eCollection 2014 Jan.
We report a case in which an effective endovascular treatment cured the worsening of dementia due to a dural arteriovenous fistula (dAVF).
A 73-year-old woman suffered for 1.5 years from gait disturbance and disorientation that were suspicious of dementia. A brain MRI revealed that her symptoms were likely due to dAVF. An angiography provided a definitive diagnosis of dural transverse-sigmoid sinus fistula. Transvenous embolization completely occluded the fistula and led to a significant improvement of her cognitive function in tandem with a restoration of the cerebral blood flow.
Endovascular treatment for dAVF is sometimes effective in treating worsening dementia, which might be due to the drastic change in cerebral blood flow in the area relevant to the cognitive function.
我们报告了一例通过有效的血管内治疗治愈了因硬脑膜动静脉瘘(dAVF)导致的痴呆症恶化的病例。
一名73岁女性因步态障碍和定向障碍遭受了1.5年的折磨,这些症状疑似痴呆症。脑部磁共振成像(MRI)显示她的症状可能是由dAVF引起的。血管造影术明确诊断为硬脑膜横窦 - 乙状窦瘘。经静脉栓塞完全闭塞了瘘管,并在脑血流恢复的同时使她的认知功能得到了显著改善。
dAVF的血管内治疗有时对治疗痴呆症恶化有效,这可能是由于与认知功能相关区域的脑血流发生了剧烈变化。