Department of Psychiatry, Case Western Reserve University School of Medicine, West Palm Beach, FL, USA.
J Sex Med. 2014 Jun;11(6):1392-422. doi: 10.1111/jsm.12504. Epub 2014 May 22.
In 2009, the International Society for Sexual Medicine (ISSM) convened a select panel of experts to develop an evidence-based set of guidelines for patients suffering from lifelong premature ejaculation (PE). That document reviewed definitions, etiology, impact on the patient and partner, assessment, and pharmacological, psychological, and combined treatments. It concluded by recognizing the continually evolving nature of clinical research and recommended a subsequent guideline review and revision every fourth year. Consistent with that recommendation, the ISSM organized a second multidisciplinary panel of experts in April 2013, which met for 2 days in Bangalore, India. This manuscript updates the previous guidelines and reports on the recommendations of the panel of experts.
The aim of this study was to develop clearly worded, practical, evidenced-based recommendations for the diagnosis and treatment of PE for family practice clinicians as well as sexual medicine experts.
A comprehensive literature review was performed.
This article contains the report of the second ISSM PE Guidelines Committee. It offers a new unified definition of PE and updates the previous treatment recommendations. Brief assessment procedures are delineated, and validated diagnostic and treatment questionnaires are reviewed. Finally, the best practices treatment recommendations are presented to guide clinicians, both familiar and unfamiliar with PE, in facilitating treatment of their patients.
Development of guidelines is an evolutionary process that continually reviews data and incorporates the best new research. We expect that ongoing research will lead to a more complete understanding of the pathophysiology as well as new efficacious and safe treatments for this sexual dysfunction. We again recommend that these guidelines be reevaluated and updated by the ISSM in 4 years.
2009 年，国际性医学会（ISSM）召集了一组精选的专家，为患有终身性早泄（PE）的患者制定了一套基于证据的指南。该文件回顾了定义、病因、对患者和伴侣的影响、评估以及药物治疗、心理治疗和联合治疗。它最后承认临床研究的性质在不断发展，并建议每四年对指南进行一次后续审查和修订。根据这一建议，ISSM 于 2013 年 4 月组织了第二次多学科专家小组，该小组在印度班加罗尔举行了为期两天的会议。这份手稿更新了以前的指南，并报告了专家组的建议。
本研究的目的是为家庭医生和性医学专家制定明确的、实用的、基于证据的 PE 诊断和治疗建议。
进行了全面的文献回顾。
本文包含第二次 ISSM PE 指南委员会的报告。它提供了一个新的统一的 PE 定义，并更新了以前的治疗建议。简要的评估程序被划定，验证的诊断和治疗问卷被审查。最后，提出了最佳实践治疗建议，以指导熟悉和不熟悉 PE 的临床医生为他们的患者提供治疗。
指南的制定是一个不断审查数据并纳入最新研究的过程。我们预计，正在进行的研究将导致对这种性功能障碍的病理生理学有更完整的了解，并为其提供新的有效和安全的治疗方法。我们再次建议 ISSM 在 4 年内重新评估和更新这些指南。
