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大鼠面后静脉间置移植:一种更具相关性的训练模型。

Rat posterior facial vein interpositional graft: a more relevant training model.

作者信息

Lee Nicolas, Daley Roger A, Cooley Brian C

机构信息

Department of Orthopaedic Surgery, Medical College of Wisconsin, Milwaukee, WI.

出版信息

Microsurgery. 2014 Nov;34(8):653-6. doi: 10.1002/micr.22278. Epub 2014 May 22.

Abstract

Microvascular training models for vein grafting most often use the rat epigastric vein interpositioned to the femoral artery. We describe the rat posterior facial vein as an alternative vein graft model; it has at least a 2:1 diametric ratio to the femoral artery and a tougher connective tissue, making it more similar to clinical vein grafting for reconstructive microsurgery. A series of 24 grafts interpositioned to the femoral artery were done using 11-12 sutures per end-to-end anastomosis and yielded early patency rates of 96% at 20 min and 92% at 2 and 4 weeks for subsets of 12 grafts. As a training model the diametric disparity provides unique challenges with clinical relevance, for which a number of different techniques for matching arterial to venous circumferences can be done.

摘要

用于静脉移植的微血管训练模型最常使用置于股动脉的大鼠腹壁静脉。我们描述了大鼠面后静脉作为一种替代静脉移植模型;它与股动脉的直径比至少为2:1,且结缔组织更坚韧,使其在重建显微外科手术中更类似于临床静脉移植。使用24根置于股动脉的移植血管,每端对端吻合使用11 - 12根缝线,对于12根移植血管的子集,在20分钟时早期通畅率为96%,在2周和4周时为92%。作为一种训练模型,直径差异带来了具有临床相关性的独特挑战,针对这一挑战,可以采用多种不同的技术来匹配动脉和静脉的周长。

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