Gupta Santosh S
Department of Magnetic Resonance Imaging, P.D. Hinduja Hospital and Medical Research Centre, Veer Savarkar Marg, Mahim, Mumbai, Maharashtra, India.
Indian J Radiol Imaging. 2014 Jan;24(1):37-43. doi: 10.4103/0971-3026.130690.
Evaluating language has been a long-standing application in functional magnetic resonance imaging (fMRI) studies, both in research and clinical circumstances, and still provides challenges. Localization of eloquent areas is important in neurosurgical cases, so that there is least possible damage to these areas during surgery, maintaining their function postoperatively, therefore providing good quality of life to the patient. Preoperative fMRI study is a non-invasive tool to localize the eloquent areas, including language, with other traditional methods generally used being invasive and at times perilous. In this article, we describe methods and various paradigms to study the language areas, in clinical neurosurgical cases, along with illustrations of cases from our institute.
在研究和临床环境中,评估语言一直是功能磁共振成像(fMRI)研究中的一项长期应用,并且仍然存在挑战。在神经外科手术病例中,明确区域的定位很重要,这样在手术期间对这些区域的损伤才能降至最低,术后保持其功能,从而为患者提供良好的生活质量。术前fMRI研究是一种用于定位包括语言区域在内的明确区域的非侵入性工具,而通常使用的其他传统方法具有侵入性,有时甚至有风险。在本文中,我们描述了在临床神经外科病例中研究语言区域的方法和各种范式,并展示了我们研究所的病例。