Agarwal Shruti, Sair Haris I, Gujar Sachin, Pillai Jay J
Division of Neuroradiology, Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD.
Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Top Magn Reson Imaging. 2019 Aug;28(4):225-233. doi: 10.1097/RMR.0000000000000216.
Clinical use of blood oxygen level dependent (BOLD) functional magnetic resonance imaging (fMRI) is a relatively new phenomenon, with only about 3 decades of collective experience. Nevertheless, task-based BOLD fMRI has been widely accepted for presurgical planning, over traditional methods, which are invasive and at times perilous. Many studies have demonstrated the ability of BOLD fMRI to make substantial clinical impact with respect to surgical planning and preoperative risk assessment, especially to localize the eloquent motor and visual areas. Reproducibility and repeatability of language fMRI are important in the assessment of its clinical usefulness. There are national efforts currently underway to standardize language fMRI. The American Society of Functional Neuroradiology (ASFNR) has recently provided guidelines on fMRI paradigm algorithms for presurgical language assessment for language lateralization and localization. In this review article, we provide a comprehensive overview of current standards of language fMRI mapping and its reproducibility.
血氧水平依赖（BOLD）功能磁共振成像（fMRI）的临床应用是一个相对较新的现象，仅有大约30年的集体经验。然而，基于任务的BOLD fMRI已被广泛应用于术前规划，优于传统方法，传统方法具有侵入性且有时存在风险。许多研究表明，BOLD fMRI在手术规划和术前风险评估方面，尤其是在明确运动和视觉功能区定位方面，能够产生重大的临床影响。语言fMRI的可重复性和再现性对于评估其临床实用性很重要。目前正在进行全国性的努力以规范语言fMRI。美国功能神经放射学会（ASFNR）最近提供了关于fMRI范式算法的指南，用于术前语言评估以确定语言优势半球和定位。在这篇综述文章中，我们全面概述了当前语言fMRI映射的标准及其可重复性。
