来自中国的一株肠道病毒75型分离株的全基因组序列分析
Complete genome sequence analysis of an enterovirus 75 isolate from China.
作者信息
Tao Zexin, Cui Ning, Lin Xiaojuan, Wang Haiyan, Song Lizhi, Li Yan, Zhang Li, Liu Xiaolin, Wang Suting, Xu Aiqiang, Song Yanyan
机构信息
Academy of Preventive Medicine, Shandong University, Jinan, People's Republic of China.
出版信息
Arch Virol. 2014 Oct;159(10):2809-13. doi: 10.1007/s00705-014-2014-6. Epub 2014 May 23.
Enterovirus 75 (EV-B75) is a member of the species Enterovirus B (EV-B). So far, only the complete genome of the prototype strain from the United States is available. Here, we report the genome sequence of an EV-B75 isolate from an acute flaccid paralysis patient in China. Sequence analysis revealed high nucleotide sequence divergence from foreign EV-B75 strains and suggested several recombination events with other serotypes of EV-B.
肠道病毒75型（EV-B75）是肠道病毒B种（EV-B）的一个成员。到目前为止，仅有来自美国的原型株的完整基因组序列。在此，我们报告了一株从中国一名急性弛缓性麻痹患者分离出的EV-B75的基因组序列。序列分析显示其与国外EV-B75毒株存在高度核苷酸序列差异，并提示其与其他EV-B血清型发生了多次重组事件。
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