• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

帕唑帕尼治疗转移性肾细胞癌长期存活男性的病例报告。

Case report of a long-surviving man with metastatic renal cell carcinoma treated with pazopanib.

作者信息

Ratta Raffaele, Santini Daniele

出版信息

Tumori. 2014 Mar-Apr;100(2):e59-62. doi: 10.1177/030089161410000227.

DOI:10.1177/030089161410000227
PMID:24852879
Abstract

Renal cell carcinoma is the most common type of kidney cancer in adults. It accounts for approximately 3% of adult malignancies and 90-95% of neoplasms arising from the kidney. At the moment several biological agents are used for the treatment of metastatic renal cell carcinoma. We describe the case of a man who has been treated with pazopanib (Votrient) for metastatic renal cell carcinoma since July 2011. At the time of writing, the patient is still receiving treatment (29 months) and is showing a long-lasting response with a favorable safety profile. This is an excellent example of chronic neoplastic disease in a patient who can be defined as long-surviving.

摘要

肾细胞癌是成人中最常见的肾癌类型。它约占成人恶性肿瘤的3%,以及肾脏肿瘤的90 - 95%。目前有几种生物制剂用于治疗转移性肾细胞癌。我们描述了一名自2011年7月起接受帕唑帕尼(维全特)治疗转移性肾细胞癌的男性病例。在撰写本文时,该患者仍在接受治疗(29个月),并表现出持久的反应且安全性良好。这是一名可被定义为长期存活患者的慢性肿瘤疾病的极佳例子。

相似文献

1
Case report of a long-surviving man with metastatic renal cell carcinoma treated with pazopanib.帕唑帕尼治疗转移性肾细胞癌长期存活男性的病例报告。
Tumori. 2014 Mar-Apr;100(2):e59-62. doi: 10.1177/030089161410000227.
2
Targeted therapy in renal carcinoma: a case of long-term effect with complete control of toxicity.
Tumori. 2014 Nov-Dec;100(6):e293-7. doi: 10.1700/1778.19302.
3
Cardiac metastasis from renal cell carcinoma successfully treated with pazopanib: impact of TKIs' antiangiogenic activity.帕唑帕尼成功治疗肾细胞癌心脏转移:酪氨酸激酶抑制剂抗血管生成活性的影响
Tumori. 2014 Nov-Dec;100(6):e298-300. doi: 10.1700/1778.19304.
4
Good tolerability, long-term survival and easy management of side effects in a patient with metastatic renal cell carcinoma treated with pazopanib.帕唑帕尼治疗转移性肾细胞癌患者时耐受性良好、长期生存且副作用易于管理。
Tumori. 2014 Nov-Dec;100(6):e301-4. doi: 10.1700/1778.19306.
5
Long-term response to pazopanib in an elderly man with mRCC. A case report.一位老年男性转移性肾细胞癌患者对帕唑帕尼的长期反应。病例报告。
Tumori. 2014 Nov-Dec;100(6):e305-8. doi: 10.1700/1778.19308.
6
Outcomes of unselected patients with metastatic clear-cell renal cell carcinoma treated with first-line pazopanib therapy followed by vascular endothelial growth factor receptor tyrosine kinase inhibitors or mammalian target of rapamycin inhibitors: a single institution experience.一线使用帕唑帕尼治疗,随后使用血管内皮生长因子受体酪氨酸激酶抑制剂或雷帕霉素靶蛋白抑制剂治疗的未经选择的转移性透明细胞肾细胞癌患者的结局:单机构经验
BJU Int. 2016 Aug;118(2):264-71. doi: 10.1111/bju.13374. Epub 2015 Dec 13.
7
[Another approach to targeted therapy of patients with metastatic renal carcinoma with progression in treatment with pazopanib:expert assessment by the Czech Cooperative Group for Metastatic Renal Carcinoma].[帕唑帕尼治疗转移性肾癌患者进展后的靶向治疗的另一种方法:捷克转移性肾癌合作组的专家评估]
Klin Onkol. 2013;26(1):55-7.
8
[First Hungarian experience with pazopanib therapy for patients with metastatic renal cancer].[匈牙利首次使用帕唑帕尼治疗转移性肾癌患者的经验]
Magy Onkol. 2013 Sep;57(3):173-6. Epub 2013 Aug 9.
9
Targeted therapies: treating advanced kidney cancer-miles to go before we sleep.靶向治疗:治疗晚期肾癌——任重道远。
Nat Rev Clin Oncol. 2013 Nov;10(11):614-5. doi: 10.1038/nrclinonc.2013.183. Epub 2013 Oct 15.
10
Uveal metastasis and myasthenia gravis in a patient with recurrent renal cell carcinoma treated with pazopanib.帕唑帕尼治疗复发性肾细胞癌患者出现葡萄膜转移和重症肌无力。
Clin Genitourin Cancer. 2014 Aug;12(4):e143-6. doi: 10.1016/j.clgc.2014.02.002. Epub 2014 Feb 21.