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The History of the AutoChemist®: From Vision to Reality.自动化学分析仪®的历史:从愿景到现实。
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Mayo Clin Proc. 2009;84(1):38-42. doi: 10.4065/84.1.38.
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Revisiting Wilson and Jungner in the genomic age: a review of screening criteria over the past 40 years.基因组时代对威尔逊和荣格纳标准的再审视:过去40年筛查标准综述
Bull World Health Organ. 2008 Apr;86(4):317-9. doi: 10.2471/blt.07.050112.
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[Chemical health control. II. Practical aspects with results from selected material].[化学健康控制。二。所选材料结果的实践方面]
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[Chemical health control. I. An aid to the private physician's health examination, a further resource for group examinations in health centers and a method of choice in general examination of the population].[化学健康控制。一、对私人医生健康检查的辅助,健康中心团体检查的进一步资源以及人群一般检查的首选方法]
Sven Lakartidn. 1962 Aug 9;59:2297-309.
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An automatic method for colorimetric analysis.一种比色分析的自动方法。
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Periodic health examinations using an automated multitest laboratory.使用自动化多项检测实验室进行定期健康检查。
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数据系统自动化学分析仪(ACH)和自动化学分析仪 - PRISMA(PRISMA®)的历史:1964年至1986年

The History of the Data Systems AutoChemist® (ACH) and AutoChemist- PRISMA (PRISMA®): from 1964 to 1986.

作者信息

Ohlsén L, Jungner I, Peterson H E

机构信息

Leif Ohlsén, Stockholm, Sweden, E-mail:

出版信息

Yearb Med Inform. 2014 May 22;9(1):244-54. doi: 10.15265/IY-2014-0029.

DOI:10.15265/IY-2014-0029
PMID:24853032
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4287085/
Abstract

OBJECTIVES

This paper presents the history of data system development steps (1964 - 1986) for the clinical analyzers AutoChemist®, and its successor AutoChemist PRISMA® (PRogrammable Individually Selective Modular Analyzer). The paper also partly recounts the history of development steps of the minicomputer PDP 8 from Digital Equipment. The first PDP 8 had 4 core memory boards of 1 K each and was large as a typical oven baking sheet and about 10 years later, PDP 8 was a "one chip microcomputer" with a 32 K memory chip. The fast developments of PDP 8 come to have a strong influence on the development of the data system for AutoChemist. Five major releases of the software were made during this period (1-5 MIACH).

RESULTS

The most important aims were not only to calculate the results, but also be able to monitor their quality and automatically manage the orders, store the results in digital form for later statistical analysis and distribute the results to the physician in charge of the patient using thesame computer as the analyzer. Another result of the data system was the ability to customize AutoChemist to handle sample identification by using bar codes and the presentation of results to different types of laboratories.

CONCLUSIONS

Digital Equipment launched the PDP 8 just as a new minicomputer was desperately needed. No other known alternatives were available at the time. This was to become a key success factor for AutoChemist. That the AutoChemist with such a high capacity required a computer for data collection was obvious already in the early 1960s. That computer development would be so rapid and that one would be able to accomplish so much with a data system was even suspicious at the time. In total, 75; AutoChemist (31) and PRISMA (44) were delivered Worldwide. The last PRISMA was delivered in 1987 to the Veteran Hospital Houston, TX USA.

摘要

目标

本文介绍了临床分析仪AutoChemist®及其继任产品AutoChemist PRISMA®(可编程独立选择性模块化分析仪)的数据系统开发步骤(1964 - 1986年)的历史。本文还部分讲述了数字设备公司的小型计算机PDP 8的开发步骤历史。第一台PDP 8有4个1K的核心存储板,大小如典型的烤盘,大约10年后,PDP 8成为了带有32K存储芯片的“单芯片微型计算机”。PDP 8的快速发展对AutoChemist数据系统的开发产生了重大影响。在此期间发布了五个主要版本的软件(1 - 5 MIACH)。

结果

最重要的目标不仅是计算结果,还要能够监测其质量并自动管理订单,以数字形式存储结果以便后续统计分析,并使用与分析仪相同的计算机将结果分发给负责该患者的医生。数据系统的另一个成果是能够定制AutoChemist,以使用条形码处理样本识别并将结果呈现给不同类型的实验室。

结论

数字设备公司推出PDP 8时,恰逢急需一款新型小型计算机。当时没有其他已知的替代品。这成为了AutoChemist成功的关键因素。早在20世纪60年代初,具有如此高容量的AutoChemist需要一台计算机来进行数据收集就很明显了。当时,计算机发展如此迅速,而且一个数据系统能够完成如此多的任务甚至令人怀疑。全球共交付了75台AutoChemist(31台)和PRISMA(44台)。最后一台PRISMA于1987年交付给美国德克萨斯州休斯顿的退伍军人医院。