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自动化学分析仪®的历史:从愿景到现实。

The History of the AutoChemist®: From Vision to Reality.

作者信息

Peterson H E, Jungner I

机构信息

Hans E. Peterson MD, PhD, Stockholm, Sweden, E-mail:

出版信息

Yearb Med Inform. 2014 May 22;9(1):235-43. doi: 10.15265/IY-2014-0028.

Abstract

OBJECTIVES

This paper discusses the early history and development of a clinical analyser system in Sweden (AutoChemist, 1965). It highlights the importance of such high capacity system both for clinical use and health care screening. The device was developed to assure the quality of results and to automatically handle the orders, store the results in digital form for later statistical analyses and distribute the results to the patients' physicians by using the computer used for the analyser.

RESULTS

The most important result of the construction of an analyser able to produce analytical results on a mass scale was the development of a mechanical multi-channel analyser for clinical laboratories that handled discrete sample technology and could prevent carry-over to the next test samples while incorporating computer technology to improve the quality of test results. The AutoChemist could handle 135 samples per hour in an 8-hour shift and up to 24 possible analyses channels resulting in 3,200 results per hour. Later versions would double this capacity. Some customers used the equipment 24 hours per day.

CONCLUSIONS

With a capacity of 3,000 to 6,000 analyses per hour, pneumatic driven pipettes, special units for corrosive liquids or special activities, and an integrated computer, the AutoChemist system was unique and the largest of its kind for many years. Its follower - The AutoChemist PRISMA (PRogrammable Individually Selective Modular Analyzer) - was smaller in size but had a higher capacity. Both analysers established new standards of operation for clinical laboratories and encouraged others to use new technologies for building new analysers.

摘要

目的

本文探讨了瑞典一种临床分析仪系统(AutoChemist,1965年)的早期历史与发展。它强调了这种高容量系统对于临床应用和医疗筛查的重要性。该设备的研发旨在确保结果质量,自动处理订单,以数字形式存储结果以便后续进行统计分析,并通过用于分析仪的计算机将结果分发给患者的医生。

结果

构建一个能够大规模产生分析结果的分析仪的最重要成果,是开发了一种用于临床实验室的机械多通道分析仪,该分析仪采用离散样本技术,能够防止交叉污染到下一个测试样本,同时整合计算机技术以提高测试结果的质量。AutoChemist在8小时轮班中每小时可处理135个样本,最多有24个可能的分析通道,每小时可产生3200个结果。后续版本的处理能力将翻倍。一些客户每天24小时使用该设备。

结论

AutoChemist系统每小时具备3000至6000次分析能力,采用气动移液器、用于腐蚀性液体或特殊操作的特殊单元以及集成计算机,多年来它一直是同类产品中独一无二且规模最大的。其后续型号——AutoChemist PRISMA(可编程独立选择性模块化分析仪)——体积较小但处理能力更强。这两款分析仪都为临床实验室确立了新的操作标准,并促使其他机构采用新技术来构建新的分析仪。

相似文献

6
Evaluation of the computing aspects of automatic analysers.自动分析仪计算方面的评估。
Ann Clin Biochem. 1986 Sep;23 ( Pt 5):585-9. doi: 10.1177/000456328602300516.

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