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[全胃肠外营养配方对营养不良患者术前喂养代谢反应的影响]

[The effect of the TPN formulation on the the metabolic response to preoperative feeding in malnourished patients].

作者信息

Sitges Serra A, Gil Egea M J, Martínez Ródenas F

出版信息

Nutr Hosp. 1989 Jul-Sep;4(4):184-8.

PMID:2485347
Abstract

There has long existed proof that complications and mortality in patients suffering from malnutrition can be reduced by subjecting them to parenteral nutrition prior to surgery. However, it is also true that some patients do not show an improvement, and in fact that their condition worsens after artificial forced feeding during the preoperative period. Presentation of the preliminary results of a randomized prospective study performed on two groups of patients with malnutrition who were fed with different formula of parenteral nutrition. The aim was to investigate the influence of the water, sodium and glucose content of the diet on weight gain, the balance of water and sodium and changes in the concentration of albumin. 14 patients on whom major surgery was to be performed were studied over a 10-day period. Patients with metabolic alterations were excluded. The patients were randomized and some received a standard formula of parenteral nutrition and others a modified formula. It was shown that parenteral nutrition composition may have an important effect on the nutritional response in patients suffering from malnutrition. The intravenous modified diet, formulated in accordance with theoretical weight parameters, was proved to be more advantageous compared with a formula containing standard levels of water, sodium and glucose.

摘要

长期以来,有证据表明,营养不良患者在手术前接受肠外营养可以降低并发症和死亡率。然而,确实有一些患者没有改善,事实上,他们在术前人工强制喂养后的病情反而恶化。本文介绍了一项对两组营养不良患者进行不同配方肠外营养喂养的随机前瞻性研究的初步结果。目的是研究饮食中的水、钠和葡萄糖含量对体重增加、水钠平衡以及白蛋白浓度变化的影响。在10天的时间里对14名计划进行大手术的患者进行了研究。排除有代谢改变的患者。将患者随机分组,一些患者接受标准配方的肠外营养,另一些患者接受改良配方。结果表明,肠外营养成分可能对营养不良患者的营养反应有重要影响。根据理论体重参数配制的静脉改良饮食被证明比含有标准水平水、钠和葡萄糖的配方更具优势。

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Nutr Hosp. 1989 Jul-Sep;4(4):184-8.
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