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术前肠外营养对营养不良患者免疫反应能力的影响(术前肠外营养与免疫)

[The effect of preoperative parenteral nutrition on the capacity of the immune response in malnourished patients (preoperative parenteral nutrition and immunity)].

作者信息

Celaya Pérez S, Navarro M, Román A, Salinas J C, Larrad L, Lasierra M P, Lozano Mantecón R

出版信息

Nutr Hosp. 1989 Apr-Jun;4(3):145-8.

PMID:2485364
Abstract

The objective of this study is to evaluate the response of the subpopulations of lymphocytes and IGs to the administration of total parenteral nutrition for 7 days in 26 patients suffering from malnutrition, 12 of whom had digestive neoplasia and 14 non-neoplastic gastrointestinal disorders. Following the total parenteral nutrition, a significant increase in the percentage of T-helper lymphocytes was noted, and an improvement in the OKT4/OKT8 quotient, as well as in the IgA and the C4 fraction of the complement. The existence of neoplastic conditions did not have a significant effect on the variations in the parameters studied. The presence of lipids in the parenteral nutrition diet did not affect the subpopulations of lymphocytes.

摘要

本研究的目的是评估26例营养不良患者在接受7天全胃肠外营养后淋巴细胞亚群和免疫球蛋白(IGs)的反应,其中12例患有消化系肿瘤,14例患有非肿瘤性胃肠道疾病。全胃肠外营养后,观察到辅助性T淋巴细胞百分比显著增加,OKT4/OKT8比值、免疫球蛋白A(IgA)以及补体C4成分有所改善。肿瘤情况的存在对所研究参数的变化没有显著影响。肠外营养饮食中脂质的存在不影响淋巴细胞亚群。

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