Roa I, Araya J C, Soza D, Thomas K
Rev Chil Pediatr. 1989 Mar-Apr;60(2):97-9.
A case of malignant histiocytosis in a two year old boy is reported. His main clinical features were fever, lymphadenopathy, hepatomegaly and splenomegaly. Lymph node biopsy showed a sinusoidal type of lymph node infiltration, histiocytes of malignant aspect and erythrophagocytosis. Liver infiltration with tumoral cells was demonstrated by needle biopsy. The clinical evolution was rapidly progressive and after six months of chemotherapy he died of intercurrent respiratory infection.
报告了一名两岁男孩的恶性组织细胞增多症病例。其主要临床特征为发热、淋巴结病、肝肿大和脾肿大。淋巴结活检显示为窦状型淋巴结浸润、具有恶性特征的组织细胞和红细胞吞噬现象。针吸活检证实肝脏有肿瘤细胞浸润。临床病程进展迅速，化疗六个月后，他死于并发的呼吸道感染。
