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中国老年患者髋部骨折外周神经阻滞与全身麻醉的比较结果

Comparative outcomes of peripheral nerve blocks versus general anesthesia for hip fractures in geriatric Chinese patients.

作者信息

Liu Jun Le, Wang Xiao Lin, Gong Mao Wei, Mai Hai Xing, Pei Shu Jun, Yuan Wei Xiu, Zhang Hong

机构信息

Anesthesia and Operation Center, Chinese People's Liberation Army General Hospital and Medical School of Chinese People's Liberation Army, Beijing, People's Republic of China.

Department of Urology, Affiliated Hospital of Academy of Military Medical Sciences, Beijing, People's Republic of China.

出版信息

Patient Prefer Adherence. 2014 May 7;8:651-9. doi: 10.2147/PPA.S61903. eCollection 2014.

Abstract

BACKGROUND

Geriatric patients undergoing hemiarthroplasty for hip fractures have unacceptably high rates of postoperative complications and mortality. Whether anesthesia type can affect the outcomes has still been inconclusive.

OBJECTIVES

We compared general anesthesia (GA) and peripheral nerve blocks (PNBs) on postoperative complications and mortality in elderly patients with femoral neck fractures (FNF) undergoing hemiarthroplasty.

MATERIALS AND METHODS

This retrospective study involved data collection from an electronic database. Two hundred and seventeen patients underwent hemiarthroplasty for FNF between January 2008 and December 2012 at the Chinese People's Liberation Army General Hospital. Data on mortality within in-hospital, 30-day, and 1-year, complications, comorbidities, blood loss and transfusion, operative time, postoperative hospital length of stay, intensive care unit admission, and hospital charge were collected and analyzed. Univariate and multivariate Cox regression analyses of all variables were used for 30-day and 1-year mortality.

RESULTS

Seventy-two patients receiving GA and 145 receiving PNBs were eventually submitted and analyzed. Mortality was 6.9%, 14.7%, and 23.5% at in-hospital, 30-day, and 1-year, respectively postoperatively, while mortality and cardiovascular complications did not differ between the two anesthetic techniques. Preoperative comorbidities and intraoperative parameters were not statistically different except that patients receiving GA were more likely to have dementia (χ (2)=10.45, P=0.001). The most common complications were acute cardiovascular events, electrolyte disturbances, and delirium. Postoperative acute respiratory events and hypoxemia both were also common, but no differences were found between groups (χ (2)=0.68, P=0.410; χ (2)=3.42, P=0.065, respectively). Key factors negatively influencing mortality included: age, male gender, American Society of Anesthesiologists status, dementia, perioperative cardiovascular events and respiratory events, postoperative stroke, myocardial infarction, and hypoxia.

CONCLUSION

Mortality and postoperative complications are not statistically significantly different between PNBs and GA among eldery patients undergoing hemiarthroplasty for FNF.

摘要

背景

因髋部骨折接受半髋关节置换术的老年患者术后并发症和死亡率高得令人难以接受。麻醉类型是否会影响手术结果尚无定论。

目的

我们比较了全身麻醉(GA)和外周神经阻滞(PNB)对接受半髋关节置换术的老年股骨颈骨折(FNF)患者术后并发症和死亡率的影响。

材料与方法

这项回顾性研究涉及从电子数据库收集数据。2008年1月至2012年12月期间,217例患者在中国人民解放军总医院因FNF接受了半髋关节置换术。收集并分析了患者的院内、30天和1年死亡率、并发症、合并症、失血量和输血量、手术时间、术后住院时间、重症监护病房入住情况和住院费用等数据。对所有变量进行单因素和多因素Cox回归分析,以评估30天和1年死亡率。

结果

最终纳入72例接受GA的患者和145例接受PNB的患者进行分析。术后院内、30天和1年死亡率分别为6.9%、14.7%和23.5%,两种麻醉技术的死亡率和心血管并发症无差异。术前合并症和术中参数无统计学差异,但接受GA的患者更易患痴呆(χ(2)=10.45,P=0.001)。最常见的并发症是急性心血管事件、电解质紊乱和谵妄。术后急性呼吸事件和低氧血症也很常见,但两组间无差异(χ(2)=0.68,P=0.410;χ(2)=3.42,P=0.065)。对死亡率有负面影响的关键因素包括:年龄、男性、美国麻醉医师协会分级、痴呆、围手术期心血管事件和呼吸事件、术后中风、心肌梗死和低氧血症。

结论

在接受FNF半髋关节置换术的老年患者中,PNB和GA的死亡率和术后并发症在统计学上无显著差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4085/4019620/88622240222e/ppa-8-651Fig1.jpg

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