呼吸道感染中的非结核分枝杆菌：诊断与鉴定进展
Nontuberculous mycobacteria in respiratory infections: advances in diagnosis and identification.
作者信息
Somoskovi Akos, Salfinger Max
机构信息
Institute of Medical Microbiology, Swiss National Reference Center for Mycobacteriology, University of Zuirch, Gloriastrasse 30/32, CH-8006, Zurich, Switzerland.
Department of Medicine, National Jewish Health, K420, 1400 Jackson Street, Denver, CO 80206, USA.
出版信息
Clin Lab Med. 2014 Jun;34(2):271-95. doi: 10.1016/j.cll.2014.03.001.
An urgent question that needs to be addressed rapidly by the mycobacteriology laboratory is whether Mycobacterium tuberculosis complex or NTM is involved. NAA assays are excellent tools for the purpose, and can be used directly on the clinical specimens of patients suspected of having mycobacterial disease, allowing same-day reporting of results. The CDC recommends using both liquid and solid media for growth detection of mycobacteria to decrease the time to detection and to increase the yield of growth detection. DNA sequencing of variable genomic regions offers a rapid, accurate, and relatively inexpensive method for the identification of mycobacteria.
分枝杆菌实验室需要迅速解决的一个紧迫问题是是否涉及结核分枝杆菌复合群或非结核分枝杆菌。核酸扩增检测（NAA）测定法是用于此目的的出色工具，可直接用于疑似患有分枝杆菌病患者的临床标本，实现结果的当日报告。美国疾病控制与预防中心（CDC）建议使用液体和固体培养基来检测分枝杆菌的生长，以缩短检测时间并提高生长检测的产量。可变基因组区域的DNA测序为分枝杆菌的鉴定提供了一种快速、准确且相对廉价的方法。
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