Mathur Aarti, Olson Matthew T, Zeiger Martha A
Department of Surgery, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA.
Department of Pathology, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA.
Surg Clin North Am. 2014 Jun;94(3):499-513. doi: 10.1016/j.suc.2014.02.005. Epub 2014 Apr 3.
Follicular lesions of the thyroid encompass a wide spectrum of diseases with clinicopathologic overlap, including benign follicular adenoma, malignant follicular carcinoma, and follicular variant of papillary cancer. This review addresses the clinical presentation, preoperative diagnosis in the era of molecular markers, pathologic diagnosis, treatment, and prognosis of follicular lesions, taking into account the frequent controversy about definitive histologic diagnoses.
甲状腺滤泡性病变涵盖了一系列具有临床病理重叠的疾病，包括良性滤泡性腺瘤、恶性滤泡癌以及乳头状癌的滤泡变体。鉴于在明确组织学诊断方面经常存在争议，本综述探讨了滤泡性病变的临床表现、分子标志物时代的术前诊断、病理诊断、治疗及预后。
