Wong John K F, Nortley Ross, Andrews Thomasin, D'Cruz David
The Louise Coote Lupus Unit, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Department of Neurology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
BMJ Case Rep. 2014 May 23;2014:bcr2012008038. doi: 10.1136/bcr-2012-008038.
A 54-year-old woman diagnosed with primary Sjögren's syndrome in 2007 presented with a 1-year history of visual hallucinations requiring admission to a psychiatric unit. The hallucinations resolved while on olanzapine and hydroxychloroquine but recurred when they were stopped. Despite restarting olanzapine, her visual hallucinations persisted. When she started a tapering dose of prednisolone, all the hallucinations resolved. This report adds to the small literature on psychiatric manifestations of Sjögren's syndrome and provides evidence that low-dose corticosteroids may be an effective treatment for this manifestation.
一名54岁女性于2007年被诊断为原发性干燥综合征，出现视幻觉1年，需入住精神科病房。在服用奥氮平和羟氯喹期间幻觉消失，但停药后复发。尽管重新开始服用奥氮平，她的视幻觉仍持续存在。当她开始逐渐减少泼尼松龙剂量时，所有幻觉都消失了。本报告补充了关于干燥综合征精神症状的少量文献，并提供了证据表明低剂量皮质类固醇可能是治疗这种症状的有效方法。
