Setji Tracy L, Brown Ann J
Division of Endocrinology, Department of Medicine, Duke University Medical Center, Durham, NC.
Division of Endocrinology, Department of Medicine, Duke University Medical Center, Durham, NC.
Am J Med. 2014 Oct;127(10):912-9. doi: 10.1016/j.amjmed.2014.04.017. Epub 2014 May 21.
Polycystic ovary syndrome is now a well-recognized condition affecting 6%-25% of reproductive-aged women, depending on the definition. Over the past 3 decades, research has launched it from relative medical obscurity to a condition increasingly recognized as common in internal medicine practices. It affects multiple systems, and requires a comprehensive perspective on health care for effective treatment. Metabolic derangements and associated complications include insulin resistance and diabetes, hyperlipidemia, hypertension, fatty liver, metabolic syndrome, and sleep apnea. Reproductive complications include oligo-/amenorrhea, sub-fertility, endometrial hyperplasia, and cancer. Associated psychosocial concerns include depression and disordered eating. Additionally, cosmetic issues include hirsutism, androgenic alopecia, and acne. This review organizes this multi-system approach around the mnemonic "MY PCOS" and discusses evaluation and treatment options for the reproductive, cosmetic, and metabolic complications of this condition.
多囊卵巢综合征现在是一种广为人知的病症，根据定义，它影响着6%至25%的育龄妇女。在过去三十年里，研究已将其从相对医学上的模糊状态提升为一种在内科实践中日益被视为常见的病症。它影响多个系统，需要全面的医疗视角以进行有效治疗。代谢紊乱及相关并发症包括胰岛素抵抗和糖尿病、高脂血症、高血压、脂肪肝、代谢综合征及睡眠呼吸暂停。生殖并发症包括月经稀发/闭经、生育力低下、子宫内膜增生和癌症。相关的社会心理问题包括抑郁和饮食失调。此外，美容问题包括多毛症、雄激素性脱发和痤疮。本综述围绕助记符“MY PCOS”组织这种多系统方法，并讨论该病症生殖、美容和代谢并发症的评估及治疗选择。
