Gürgey A, Altay C, Ozgen S
Turk J Pediatr. 1989 Jul-Sep;31(3):245-7.
A sixteen-year-old male with sickle cell anemia and congenital strabismus developed malignant hyperthermia a few minutes after the administration of succinylcholine, used as the general anesthetic for corrective eye surgery. The patient's hemoglobin S level was reduced to fifteen percent before the operation. He recovered uneventfully within a few hours. Increased serum creatinine phosphokinase activity and pathological changes observed in the muscle biopsy along with strabismus suggest that the patient had an inherited susceptibility to malignant hyperthermia.
一名患有镰状细胞贫血和先天性斜视的16岁男性，在用于矫正眼部手术的全身麻醉剂琥珀酰胆碱给药几分钟后发生恶性高热。术前患者血红蛋白S水平降至15%。他在几小时内顺利康复。血清肌酸磷酸激酶活性增加以及肌肉活检中观察到的病理变化与斜视表明该患者对恶性高热具有遗传易感性。
