Rettig B, Weitz H
Anaesthesist. 1980 Feb;29(2):103-6.
An exceptionally serious case of malignant hyperthermia in a 17 year old male is presented. A detailed description of the case is given concerning symptomatology, course, laboratory data and morphologic alterations. Our patient died after 7 weeks of intensive care due to therapy resistant septicemia and coagulation disorder. Intense adynamia and advanced muscular atrophy were present. Necropsy showed regionally different extensive lysis of skeletal muscles. In the discussion the advantage of an "ice gravel" producing machine in cooling measures, the necessity of higher procaine doses and problems of long term therapy in trauma patients coincidentally affected with malignant hyperthermia, are stressed.
本文报告了一例17岁男性患者的恶性高热异常严重病例。文中详细描述了该病例的症状、病程、实验室检查数据及形态学改变。我们的患者在接受7周重症监护后，因难治性败血症和凝血功能障碍死亡。患者出现严重乏力和重度肌肉萎缩。尸检显示骨骼肌出现区域性广泛溶解。在讨论中，强调了“碎冰”制造机在降温措施中的优势、较高剂量普鲁卡因的必要性以及恶性高热合并创伤患者长期治疗中存在的问题。
