Zhuang J
Zhonghua Er Bi Yan Hou Ke Za Zhi. 1989;24(4):204-6, 253-4.
An analysis of 240 deaf-mute students revealed that the main cause of congenital deafness had been heredity (68.5%) which was different from that before 1970s. Of the patients with delayed deafness, 29.8% were hereditary. Altogether, 92 cases (38.3%) had hereditary deafness, among which, 50 cases (46 families) were of autosomal recessive and 42 cases (37 families) autosomal dominant. Thirty-eight cases (41.3%) had their deafness induced by ototoxic antibiotics. A significant familial history of high susceptibility to such antibiotics was available in 26 cases (68.4%). It is suggested that the key of deaf-prevention should be eugenics and the avoidance of ototoxic antibiotic abuse.
对240名聋哑学生的分析显示,先天性耳聋的主要原因是遗传(68.5%),这与20世纪70年代以前不同。在迟发性耳聋患者中,29.8%是遗传性的。总共有92例(38.3%)患有遗传性耳聋,其中50例(46个家庭)为常染色体隐性遗传,42例(37个家庭)为常染色体显性遗传。38例(41.3%)的耳聋是由耳毒性抗生素引起的。26例(68.4%)有对这类抗生素高度敏感的明显家族史。建议预防耳聋的关键在于优生优育以及避免滥用耳毒性抗生素。