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链霉素所致耳聋的独特遗传方式。

Unique inheritance of streptomycin-induced deafness.

作者信息

Higashi K

机构信息

Department of Otolaryngology, School of Medicine, Akita University, Japan.

出版信息

Clin Genet. 1989 Jun;35(6):433-6.

PMID:2736791
Abstract

Analysis of reported families which include two or more members with streptomycin-induced hearing loss reveals that the trait of high susceptibility of cochlea to streptomycin is transmitted primarily through females. This is not explained by ordinary Mendelian inheritance; rather it is best understood by extranuclear inheritance.

摘要

对报告的包含两名或更多链霉素诱导性听力损失成员的家族进行分析发现,耳蜗对链霉素高易感性的性状主要通过女性传递。这无法用普通的孟德尔遗传来解释;相反,最好通过核外遗传来理解。

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