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链霉素所致耳聋的独特遗传方式。

Unique inheritance of streptomycin-induced deafness.

作者信息

Higashi K

机构信息

Department of Otolaryngology, School of Medicine, Akita University, Japan.

出版信息

Clin Genet. 1989 Jun;35(6):433-6.

PMID:2736791
Abstract

Analysis of reported families which include two or more members with streptomycin-induced hearing loss reveals that the trait of high susceptibility of cochlea to streptomycin is transmitted primarily through females. This is not explained by ordinary Mendelian inheritance; rather it is best understood by extranuclear inheritance.

摘要

对报告的包含两名或更多链霉素诱导性听力损失成员的家族进行分析发现,耳蜗对链霉素高易感性的性状主要通过女性传递。这无法用普通的孟德尔遗传来解释;相反,最好通过核外遗传来理解。

相似文献

1
Unique inheritance of streptomycin-induced deafness.链霉素所致耳聋的独特遗传方式。
Clin Genet. 1989 Jun;35(6):433-6.
2
[Familial occurrence of hearing loss following streptomycin (SM) treatment].[链霉素(SM)治疗后听力损失的家族性发生情况]
Otolaryngol Pol. 2001;55(3):313-5.
3
Familial incidence of streptomycin hearing loss and hereditary weakness of the cochlea.链霉素所致听力损失的家族发病率及耳蜗遗传性衰弱
Audiology. 1971 Sep-Dec;10(5):315-22. doi: 10.3109/00206097109072568.
4
Familial aggregation of streptomycin ototoxicity: autosomal dominant inheritance?链霉素耳毒性的家族聚集性:常染色体显性遗传?
J Med Genet. 1983 Oct;20(5):357-60. doi: 10.1136/jmg.20.5.357.
5
[Factors causing deafness in deaf-mute students].[导致聋哑学生失聪的因素]
Zhonghua Er Bi Yan Hou Ke Za Zhi. 1989;24(4):204-6, 253-4.
6
[A pedigree analysis of aminoglycoside antibiotic ototoxicity in 43 families].[43个家庭中氨基糖苷类抗生素耳毒性的系谱分析]
Zhonghua Er Bi Yan Hou Ke Za Zhi. 1988;23(3):159-60.
7
Mitochondrial A7445G mutation in two pedigrees with palmoplantar keratoderma and deafness.两个患有掌跖角化症和耳聋的家系中的线粒体A7445G突变
Am J Med Genet. 1998 Jan 13;75(2):179-85.
8
Familial streptomycin ototoxicity in a South African family: a mitochondrial disorder.一个南非家庭中的家族性链霉素耳毒性:一种线粒体疾病。
J Med Genet. 1997 Nov;34(11):904-6. doi: 10.1136/jmg.34.11.904.
9
[Screening for the 1555G mutation in mitochondrial DNA in pedigrees with aminoglycoside antibiotic induced deafness].[对氨基糖苷类抗生素致聋家系中线粒体DNA 1555G突变的筛查]
Zhonghua Er Bi Yan Hou Ke Za Zhi. 1998 Apr;33(2):67-70.
10
[Deafness and gentallin].[耳聋与庆大霉素]
JFORL J Fr Otorhinolaryngol Audiophonol Chir Maxillofac. 1972 Apr;21(4):335-8.

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与氨基糖苷类药物致聋相关的线粒体突变在拉脱维亚族群中的流行情况:证据评估。
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Study of streptomycin-induced ototoxicity: protocol for a longitudinal study.链霉素诱导耳毒性的研究:一项纵向研究方案。
Springerplus. 2016 Jun 17;5(1):758. doi: 10.1186/s40064-016-2429-5. eCollection 2016.
5
A six-generation Chinese family in haplogroup B4C1C exhibits high penetrance of 1555A > G-induced hearing Loss.一个 B4C1C 单倍型家族的六代中国人中,1555A > G 致聋表现出高外显率。
BMC Med Genet. 2010 Sep 7;11:129. doi: 10.1186/1471-2350-11-129.
6
Audiological and genetic features of the mtDNA mutations.线粒体DNA突变的听力学和遗传学特征。
Acta Otolaryngol. 2008 Jul;128(7):732-8. doi: 10.1080/00016480701719011.
7
Noise-induced hearing loss in mice treated with antiretroviral drugs.接受抗逆转录病毒药物治疗的小鼠出现噪声性听力损失。
Hear Res. 2008 May;239(1-2):69-78. doi: 10.1016/j.heares.2008.01.016. Epub 2008 Feb 8.
8
Mutational analysis of the mitochondrial 12S rRNA gene in Chinese pediatric subjects with aminoglycoside-induced and non-syndromic hearing loss.中国儿童氨基糖苷类药物诱导性及非综合征性听力损失患者线粒体12S rRNA基因的突变分析
Hum Genet. 2005 Jun;117(1):9-15. doi: 10.1007/s00439-005-1276-1. Epub 2005 Apr 20.
9
[Mitochondrial hearing impairment. Background, genetic predisposition and possibilities for diagnosis].[线粒体性听力障碍。背景、遗传易感性及诊断方法]
HNO. 2004 Jun;52(6):503-9. doi: 10.1007/s00106-003-0993-9.
10
Heterogenous point mutations in the mitochondrial tRNA Ser(UCN) precursor coexisting with the A1555G mutation in deaf students from Mongolia.来自蒙古的聋哑学生中,线粒体tRNA Ser(UCN)前体的异质性点突变与A1555G突变共存。
Am J Hum Genet. 1999 Dec;65(6):1803-6. doi: 10.1086/302658.