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经口咽pH监测诊断的喉咽反流患者的嗓音问题。

Voice problems among laryngopharyngeal reflux patients diagnosed with oropharyngeal pH monitoring.

作者信息

Mesallam Tamer A, Malki Khalid H, Farahat Mohamed, Bukhari Manal, Alharethy Sami

机构信息

Department of Otolaryngology, Head and Neck Surgery, King Saud University, Riyadh, Saudi Arabia.

出版信息

Folia Phoniatr Logop. 2013;65(6):280-7. doi: 10.1159/000362835. Epub 2014 May 24.

Abstract

BACKGROUND AND OBJECTIVES

There is a lack of consensus regarding the clinical presentation and diagnosis of laryngopharyngeal reflux (LPR). The aim of this study was to explore voice-related abnormalities in a group of LPR patients, diagnosed with a 24-hour oropharyngeal pH monitoring.

PATIENTS AND METHODS

Eighty-two patients with voice-related problems participated in the study. Diagnosis of LPR was made using a 24-hour oropharyngeal pH monitoring. Patients were divided accordingly into positive and negative pH groups. Comparisons between the two groups were done, including results of clinical presentation, Voice Handicap Index-10 (VHI-10), reflux symptom index (RSI), reflux finding score (RFS), and acoustic measurements. The correlation was conducted between Ryan scores and other variables including VHI-10, RSI, and RFS.

RESULTS

Significant differences were found between the two groups for RSI and VHI-10. No significant differences were found between the two groups regarding clinical presentation, RFS or acoustic measures. Significant positive correlations were found between the Ryan composite measurements and both severity ratings (VHI-10, RSI).

CONCLUSION

LPR clinical presentation appears to be non-specific in terms of symptoms and laryngeal findings. LPR appears to have an effect on the patients' self-perception of voice problems. Further studies are needed to clarify the effect of LPR on acoustic measurements.

摘要

背景与目的

关于喉咽反流(LPR)的临床表现和诊断,目前尚无共识。本研究的目的是探讨一组经24小时口咽pH监测诊断为LPR的患者与声音相关的异常情况。

患者与方法

82名有声音相关问题的患者参与了本研究。采用24小时口咽pH监测对LPR进行诊断。患者据此分为pH阳性组和阴性组。对两组进行了比较,包括临床表现结果、嗓音障碍指数-10(VHI-10)、反流症状指数(RSI)、反流发现评分(RFS)以及声学测量。对瑞安评分与包括VHI-10、RSI和RFS在内的其他变量进行了相关性分析。

结果

两组在RSI和VHI-10方面存在显著差异。两组在临床表现、RFS或声学测量方面未发现显著差异。瑞安综合测量与两种严重程度评分(VHI-10、RSI)之间存在显著正相关。

结论

LPR的临床表现在症状和喉部检查结果方面似乎不具有特异性。LPR似乎会影响患者对嗓音问题的自我认知。需要进一步研究来阐明LPR对声学测量的影响。

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