Mesallam Tamer A, Malki Khalid H, Farahat Mohamed, Bukhari Manal, Alharethy Sami
Department of Otolaryngology, Head and Neck Surgery, King Saud University, Riyadh, Saudi Arabia.
Folia Phoniatr Logop. 2013;65(6):280-7. doi: 10.1159/000362835. Epub 2014 May 24.
There is a lack of consensus regarding the clinical presentation and diagnosis of laryngopharyngeal reflux (LPR). The aim of this study was to explore voice-related abnormalities in a group of LPR patients, diagnosed with a 24-hour oropharyngeal pH monitoring.
Eighty-two patients with voice-related problems participated in the study. Diagnosis of LPR was made using a 24-hour oropharyngeal pH monitoring. Patients were divided accordingly into positive and negative pH groups. Comparisons between the two groups were done, including results of clinical presentation, Voice Handicap Index-10 (VHI-10), reflux symptom index (RSI), reflux finding score (RFS), and acoustic measurements. The correlation was conducted between Ryan scores and other variables including VHI-10, RSI, and RFS.
Significant differences were found between the two groups for RSI and VHI-10. No significant differences were found between the two groups regarding clinical presentation, RFS or acoustic measures. Significant positive correlations were found between the Ryan composite measurements and both severity ratings (VHI-10, RSI).
LPR clinical presentation appears to be non-specific in terms of symptoms and laryngeal findings. LPR appears to have an effect on the patients' self-perception of voice problems. Further studies are needed to clarify the effect of LPR on acoustic measurements.
关于喉咽反流(LPR)的临床表现和诊断,目前尚无共识。本研究的目的是探讨一组经24小时口咽pH监测诊断为LPR的患者与声音相关的异常情况。
82名有声音相关问题的患者参与了本研究。采用24小时口咽pH监测对LPR进行诊断。患者据此分为pH阳性组和阴性组。对两组进行了比较,包括临床表现结果、嗓音障碍指数-10(VHI-10)、反流症状指数(RSI)、反流发现评分(RFS)以及声学测量。对瑞安评分与包括VHI-10、RSI和RFS在内的其他变量进行了相关性分析。
两组在RSI和VHI-10方面存在显著差异。两组在临床表现、RFS或声学测量方面未发现显著差异。瑞安综合测量与两种严重程度评分(VHI-10、RSI)之间存在显著正相关。
LPR的临床表现在症状和喉部检查结果方面似乎不具有特异性。LPR似乎会影响患者对嗓音问题的自我认知。需要进一步研究来阐明LPR对声学测量的影响。