Ramírez Daphne Anahit Morales, Jiménez Víctor Manuel Valadez, López Xochiquetzal Hernández, Ysunza Pablo Antonio
Instituto Nacional de Rehabilitacion, Mexico City, Mexico.
Department of Speech and Language Pathology, Beaumont Health System, Royal Oak, Michigan.
J Voice. 2018 May;32(3):281-284. doi: 10.1016/j.jvoice.2017.05.009. Epub 2017 Jun 5.
Laryngopharyngeal reflux (LPR) refers to the flow of gastric acid content into the laryngopharynx. It has been reported that 10% of the patients consulting an otolaryngologist present with this condition. Signs of LPR can be identified during flexible or rigid laryngoscopy. The Voice Handicap Index (VHI) is a reliable tool for detecting the impact of voice disorders, and acoustic assessment of voice including acoustic analysis of voice (AAV) and electroglottography (EGG) provide objective data of voice production and voice disorders.
This study aimed to describe changes in AAV, EGG, and VHI in patients who present with LPR compared with a matched control group of healthy subjects.
Seventeen patients with LPR were studied. A group of healthy subjects matched by age and gender without any history of voice disorder, LPR, or gastroesophageal reflux disease was assembled. Both groups of patients were studied by VHI, flexible laryngoscopy, AAV, and EGG.
All patients with LPR demonstrated abnormal VHI values. Shimmer, jitter, open quotient, and irregularity were significantly increased in the patients with LPR. Nonsignificant correlations were found between VHI scores and abnormal acoustic parameters in patients with LPR.
Although abnormal acoustic parameters of patients with LPR were not predictive of the overall VHI score, the abnormal acoustic parameters of patients with LPR suggest a decrease in adequate laryngeal control during phonation.
喉咽反流（LPR）是指胃酸成分反流至喉咽。据报道，在耳鼻喉科就诊的患者中有10%患有此病。LPR的体征可在软性或硬性喉镜检查时发现。嗓音障碍指数（VHI）是检测嗓音障碍影响的可靠工具，嗓音声学评估包括嗓音声学分析（AAV）和电声门图（EGG），可提供嗓音产生和嗓音障碍的客观数据。
本研究旨在描述与匹配的健康对照组相比，LPR患者的AAV、EGG和VHI的变化。
对17例LPR患者进行研究。组建了一组年龄和性别匹配、无任何嗓音障碍、LPR或胃食管反流病病史的健康受试者。两组患者均接受VHI、软性喉镜检查、AAV和EGG检查。
所有LPR患者的VHI值均异常。LPR患者的嗓音闪烁度、基频微扰、开放商和不规则度显著增加。LPR患者的VHI评分与异常声学参数之间无显著相关性。
虽然LPR患者的异常声学参数不能预测总体VHI评分，但LPR患者的异常声学参数提示发声时喉部控制能力下降。
