[伯氨喹和葡萄糖-6-磷酸脱氢酶缺乏所致溶血性综合征]
[Hemolytic syndrome caused by primaquine and glucose-6-phosphate dehydrogenase deficiency].
作者信息
Martínez Pérez J L, Hadad Meléndez P
出版信息
Rev Cubana Med Trop. 1989 May-Aug;41(2):299-306.
A comparative study of 1,000 travellers coming back to Cuba from malaria-endemic areas is made. Screening for deficients of glucose 6-phosphate dehydrogenase by the methylene blue test is carried out in 500 of them; the other 500 did not undergo this test and were clinically observed throughout treatment. The figures for deficients and hemolytic syndrome were similar in the two groups. In addition the distribution according to skin color and chronology of case reporting in connection with the primaquine dose administered are analyzed. This test is useful as a screening technique in our country for prevention of hemolytic anemias through primaquine treatment.
对1000名从疟疾流行地区返回古巴的旅行者进行了一项比较研究。其中500人通过亚甲蓝试验筛查葡萄糖-6-磷酸脱氢酶缺乏症；另外500人未进行此项试验，在整个治疗过程中进行临床观察。两组中缺乏症和溶血性综合征的数据相似。此外，还分析了根据肤色和报告病例的时间顺序与所服用伯氨喹剂量的关系。在我国，这项试验作为一种筛查技术，对于通过伯氨喹治疗预防溶血性贫血是有用的。
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