Suppr超能文献

清醒患者双侧玻璃体下出血:恶性疟原虫眼部受累的新表现谱。

Bilateral subhyaloid haemorrhage in a conscious patient: a new spectrum of ocular involvement by Plasmodium falciparum.

作者信息

Abdali Nasar, Malik Azharuddin Mohammed, Shamim Md Dilawez, Rizvi Syed Wajahat Ali

机构信息

Department of Medicine, Jawaharlal Nehru Medical College, Aligarh, Uttar Pradesh, India.

Department of Ophthalmology, Jawaharlal Nehru Medical College, Aligarh, Uttar Pradesh, India.

出版信息

BMJ Case Rep. 2014 May 26;2014:bcr2013202811. doi: 10.1136/bcr-2013-202811.

Abstract

A 24-year-old woman presented with a history of high-grade fever with rigours since 3 days and bilateral sudden loss of vision since 6 h. She was conscious, oriented and her vitals were stable. She had a temperature of 101°F, anaemia, thrombocytopaenia, normal white cell count and moderate splenomegaly. On testing visual activity, she could only perceive hand movements although her pupils were bilaterally equal, and normal in size and reaction. On indirect ophthalmoscopy, optic discs were normal bilaterally; however, fovea of both eyes was masked by subhyaloid haemorrhage. Peripheral smear showed gametocytes of Plasmodium falciparum. The patient was started on arteminsinin-combined therapy and advised to be in propped-up position to help resolution of the haemorrhage. The patient was afebrile in 4 days and follow-up fundus examination showed gradual resolution of the haemorrhage. After two months, the patient regained normal visual acuity in both eyes; however, it took nearly 3 months for complete resolution of the haemorrhage.

摘要

一名24岁女性,3天来有高热伴寒战病史,6小时来双眼突然失明。她神志清醒,定向力正常,生命体征稳定。体温101°F,有贫血、血小板减少,白细胞计数正常,脾脏中度肿大。检查视力时,尽管她的双侧瞳孔大小相等且对光反应正常,但她只能感知手部运动。间接检眼镜检查显示双侧视盘正常;然而,双眼的黄斑被玻璃膜下出血遮盖。外周血涂片显示恶性疟原虫配子体。患者开始接受青蒿素联合疗法,并建议采取半卧位以促进出血吸收。患者4天后体温恢复正常,随访眼底检查显示出血逐渐吸收。两个月后,患者双眼视力恢复正常;然而,出血完全吸收花费了近3个月时间。

相似文献

2
[Relapse of Plasmodium falciparum malaria in a patient treated with artesunate].
Med Mal Infect. 2006 May;36(5):288-9. doi: 10.1016/j.medmal.2005.10.012. Epub 2006 May 12.
8
No Clinical or Molecular Evidence of Plasmodium falciparum Resistance to Artesunate-Mefloquine in Northwestern Brazil.
Am J Trop Med Hyg. 2016 Jul 6;95(1):148-54. doi: 10.4269/ajtmh.16-0017. Epub 2016 Apr 11.

本文引用的文献

1
Subhyaloid hemorrhage in cerebral malaria.
J Vector Borne Dis. 2010 Dec;47(4):261-3.
2
Ophthalmoscopic findings in adult patients with severe falciparum malaria.
Ocul Immunol Inflamm. 2008 Sep-Oct;16(5):239-41. doi: 10.1080/09273940802409977.
4
Falciparum malaria induced retrobulbar neuritis.
J Postgrad Med. 2004 Apr-Jun;50(2):150.
6
Severe subconjunctival haemorrhage associated with malaria.
Bull Soc Belge Ophtalmol. 1999;271:51-3.
7
Ophthalmoscopic abnormalities in adults with falciparum malaria.
QJM. 1998 Dec;91(12):845-52. doi: 10.1093/qjmed/91.12.845.
9
Mortality and sequelae due to cerebral malaria in African children in Brazzaville, Congo.
Am J Trop Med Hyg. 1993 Feb;48(2):216-21. doi: 10.4269/ajtmh.1993.48.216.
10
Retinal hemorrhage, a common sign of prognostic significance in cerebral malaria.
Am J Trop Med Hyg. 1983 Sep;32(5):911-5. doi: 10.4269/ajtmh.1983.32.911.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验