Abdali Nasar, Malik Azharuddin Mohammed, Shamim Md Dilawez, Rizvi Syed Wajahat Ali
Department of Medicine, Jawaharlal Nehru Medical College, Aligarh, Uttar Pradesh, India.
Department of Ophthalmology, Jawaharlal Nehru Medical College, Aligarh, Uttar Pradesh, India.
BMJ Case Rep. 2014 May 26;2014:bcr2013202811. doi: 10.1136/bcr-2013-202811.
A 24-year-old woman presented with a history of high-grade fever with rigours since 3 days and bilateral sudden loss of vision since 6 h. She was conscious, oriented and her vitals were stable. She had a temperature of 101°F, anaemia, thrombocytopaenia, normal white cell count and moderate splenomegaly. On testing visual activity, she could only perceive hand movements although her pupils were bilaterally equal, and normal in size and reaction. On indirect ophthalmoscopy, optic discs were normal bilaterally; however, fovea of both eyes was masked by subhyaloid haemorrhage. Peripheral smear showed gametocytes of Plasmodium falciparum. The patient was started on arteminsinin-combined therapy and advised to be in propped-up position to help resolution of the haemorrhage. The patient was afebrile in 4 days and follow-up fundus examination showed gradual resolution of the haemorrhage. After two months, the patient regained normal visual acuity in both eyes; however, it took nearly 3 months for complete resolution of the haemorrhage.
一名24岁女性,3天来有高热伴寒战病史,6小时来双眼突然失明。她神志清醒,定向力正常,生命体征稳定。体温101°F,有贫血、血小板减少,白细胞计数正常,脾脏中度肿大。检查视力时,尽管她的双侧瞳孔大小相等且对光反应正常,但她只能感知手部运动。间接检眼镜检查显示双侧视盘正常;然而,双眼的黄斑被玻璃膜下出血遮盖。外周血涂片显示恶性疟原虫配子体。患者开始接受青蒿素联合疗法,并建议采取半卧位以促进出血吸收。患者4天后体温恢复正常,随访眼底检查显示出血逐渐吸收。两个月后,患者双眼视力恢复正常;然而,出血完全吸收花费了近3个月时间。