液态人乳强化剂可显著改善早产儿的二十二碳六烯酸和花生四烯酸状态。
Liquid human milk fortifier significantly improves docosahexaenoic and arachidonic acid status in preterm infants.
作者信息
Berseth C L, Harris C L, Wampler J L, Hoffman D R, Diersen-Schade D A
机构信息
Department of Medical Affairs, Clinical Research, Mead Johnson Nutrition, 2400 West Lloyd Expy, Evansville, IN 47721, USA.
Department of Medical Affairs, Clinical Research, Mead Johnson Nutrition, 2400 West Lloyd Expy, Evansville, IN 47721, USA.
出版信息
Prostaglandins Leukot Essent Fatty Acids. 2014 Sep;91(3):97-103. doi: 10.1016/j.plefa.2014.03.002. Epub 2014 Mar 29.
We report the fatty acid composition of mother׳s own human milk from one of the largest US cohorts of lactating mothers of preterm infants. Milk fatty acid data were used as a proxy for intake at enrollment in infants (n=150) who received human milk with a powder human milk fortifier (HMF; Control) or liquid HMF [LHMF; provided additional 12mg docosahexaenoic acid (DHA), 20mg arachidonic acid (ARA)/100mL human milk]. Mothers provided milk samples (n=129) and reported maternal DHA consumption (n=128). Infant blood samples were drawn at study completion (Study Day 28). Human milk and infant PPL fatty acids were analyzed using capillary column gas chromatography. DHA and ARA were within ranges previously published for US term and preterm human milk. Compared to Control HMF (providing no DHA or ARA), human milk fortified with LHMF significantly increased infant PPL DHA and ARA and improved preterm infant DHA and ARA status.
我们报告了美国最大的早产婴儿哺乳母亲队列之一中母亲自身母乳的脂肪酸组成。母乳脂肪酸数据被用作入组时接受添加了粉状母乳强化剂（HMF；对照组）或液态HMF [LHMF；每100毫升母乳额外提供12毫克二十二碳六烯酸（DHA）、20毫克花生四烯酸（ARA）] 的母乳的婴儿（n = 150）摄入量的替代指标。母亲们提供了母乳样本（n = 129）并报告了母亲的DHA摄入量（n = 128）。在研究结束时（研究第28天）采集婴儿血液样本。使用毛细管柱气相色谱法分析母乳和婴儿血浆磷脂脂肪酸。DHA和ARA在先前发表的美国足月儿和早产儿母乳的范围内。与对照HMF（不提供DHA或ARA）相比，添加LHMF的母乳显著增加了婴儿血浆磷脂中的DHA和ARA，并改善了早产婴儿的DHA和ARA状况。
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