Reiestad F, Kvalheim L, McIlvaine W B
Department of Anaesthesia, Ulleval Sykehus, Oslo, Norway.
Reg Anesth. 1989 Sep-Oct;14(5):244-6.
Effective pain relief was produced in 18 patients having acute or subacute thoracic herpes zoster by the intermittent administration of local anesthetics into the pleural space via a percutaneously placed catheter. The duration of treatment varied from 16 to 21 days. During this period, the intervals between subsequent doses of 20 ml of 0.5% bupivacaine with 1:200,000 epinephrine increased in all patients from two doses per 24 hours to one dose per 24 hours. Patients became pain-free between 16 and 21 days after the beginning of treatment. The catheters were then removed, and a follow-up period of more than one year showed no signs of postherpetic neuralgia in any of the 18 patients. No side effects were observed during the treatment period.
通过经皮放置的导管向胸膜腔间歇性注射局麻药，18例急性或亚急性胸段带状疱疹患者获得了有效的疼痛缓解。治疗持续时间为16至21天。在此期间，所有患者后续剂量为20 ml含1:200,000肾上腺素的0.5%布比卡因的给药间隔从每24小时两次增加到每24小时一次。患者在治疗开始后16至21天内疼痛消失。然后拔除导管，一年多的随访期显示18例患者中无一例出现带状疱疹后神经痛迹象。治疗期间未观察到副作用。
