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韩国患者白塞病眼部表现随时间的变化:20世纪90年代和21世纪的单中心经验

Changes in Ocular Manifestations of Behçet Disease in Korean Patients over Time: A Single-center Experience in the 1990s and 2000s.

作者信息

Chung Yoo-Ri, Lee Eun-So, Kim Min Ho, Lew Ho Min, Song Ji Hun

机构信息

Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine , Seoul , Korea .

出版信息

Ocul Immunol Inflamm. 2015 Apr;23(2):157-61. doi: 10.3109/09273948.2014.918154. Epub 2014 May 27.

Abstract

PURPOSE

To analyze chronological changes in ocular manifestations of Behçet's disease (BD) in Korean patients.

METHODS

Ocular findings were retrospectively analyzed from medical records of patients diagnosed with BD between 1994 and 2010 and divided into two groups according to the date of their first visit to our ophthalmology department. Group A began care between 1994 and 2000, and Group B between 2004 and 2010.

RESULTS

Fifty-six patients (83 eyes) were included in analyses. There was a significant decrease in the number of complete BD cases in Group B compared to Group A, and fewer patients had genital lesions in Group B. Mean visual acuity was better, and more patients had good vision in Group B than in Group A at the one and two year follow-up.

CONCLUSIONS

The severity of BD has decreased over the past two decades, allowing BD patients with ocular involvement to have better visual prognoses.

摘要

目的

分析韩国贝赫切特病(BD)患者眼部表现的时间变化。

方法

回顾性分析1994年至2010年间诊断为BD的患者的病历中的眼部检查结果,并根据他们首次就诊于我们眼科的日期分为两组。A组于1994年至2000年间开始治疗,B组于2004年至2010年间开始治疗。

结果

56例患者(83只眼)纳入分析。与A组相比,B组中完全型BD病例数显著减少,B组中生殖器病变患者较少。在1年和2年随访时,B组的平均视力更好,视力良好的患者比A组更多。

结论

在过去二十年中,BD的严重程度有所降低,使有眼部受累的BD患者有更好的视力预后。

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