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[赠卵输卵管内移植术:不育夫妇的生育现实]

[GIFT: reproductive reality for the sterile couple].

作者信息

Hernández Ayup S, Santos Haliscak R, García Martínez M, Morales Caballero F, Loret de Mola Gutiérrez R, Galache Vega P

出版信息

Ginecol Obstet Mex. 1989 Nov;57:315-9.

PMID:2486971
Abstract

From June 1987 thru December 1988, 72 patients entered our gamete intrafallopian transfer (GIFT) program. The average age of our patients was 28 years with of infertility. The causes for being selected to the program were: Unknown (14), Endometriosis (14), Male (13), Ovarian (5), Cervical (9), Tubo-peritoneal (6) and oocyte donation (11). Different follicular stimulation protocols were used, with combinations of clomiphene citrate, human menopausal gonadotropins (hMG) and follicle stimulating hormone (FSH). Monitoring by serial ultrasound scanning until two or more follicles were 16-18 mm and estradiol levels were over 700 pg/ml, after which 10,000 IU of human chorionic gonadotropins (hCG) were injected. After 36 hrs oocyte retrieval was performed. There were 19 clinical pregnancies (26.4%). We feel that this new technique offers a bright and promising future for our infertile population.

摘要

从1987年6月到1988年12月,72例患者进入了我们的配子输卵管内移植(GIFT)项目。我们的患者平均年龄为28岁,患有不孕症。入选该项目的原因有:不明原因(14例)、子宫内膜异位症(14例)、男性因素(13例)、卵巢因素(5例)、宫颈因素(9例)、输卵管-腹膜因素(6例)和卵母细胞捐赠(11例)。采用了不同的卵泡刺激方案,联合使用枸橼酸氯米芬、人绝经期促性腺激素(hMG)和卵泡刺激素(FSH)。通过连续超声扫描进行监测,直到有两个或更多卵泡直径达到16 - 18毫米且雌二醇水平超过700皮克/毫升,之后注射10000国际单位的人绒毛膜促性腺激素(hCG)。36小时后进行卵母细胞采集。共有19例临床妊娠(26.4%)。我们认为这项新技术为我们的不孕患者群体带来了光明且充满希望的未来。

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