Chen Xiang-Jun, Huang Ying-De, Li Nian, Chen Min, Liu Fang, Pu Dan, Zhou Tao-You
Department of Medical Quality Control, West China Hospital, Sichuan University, Chengdu, China E-mail : drchan_hxyy@mcwcums. com.
Asian Pac J Cancer Prev. 2014;15(8):3503-5. doi: 10.7314/apjcp.2014.15.8.3503.
Interleukin-33 (IL-33) has recently been implicated in tumor development.
Data was obtained from PubMed, EMBASE, Clinical trial, Cochrane Library, Web of Science, CNKI and Wanfang databases. After quality assessment and data extraction, a meta-analysis was performed using Review Manager 5. 2 software.
There were eight documents included in this meta-analysis. The results showed IL33 levels to be higher in tumor patients than that in health people, but no correlations tumor stage, metastasis and survival time of tumor patients were evident.
IL33 may be useful as an alarm factor in tumor detection and prognosis.
白细胞介素-33（IL-33）最近被认为与肿瘤发展有关。
数据来源于PubMed、EMBASE、临床试验、Cochrane图书馆、科学网、中国知网和万方数据库。经过质量评估和数据提取后，使用Review Manager 5.2软件进行荟萃分析。
该荟萃分析纳入了8篇文献。结果显示，肿瘤患者的IL33水平高于健康人，但与肿瘤患者的肿瘤分期、转移和生存时间无明显相关性。
IL33可能作为肿瘤检测和预后的警示因子。
