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Comparative evaluation of acute toxicity and antitumor activity of IF-XXV preparation and holoxan.

作者信息

Kuśnierczyk H, Matuszyk J, Radzikowski C

机构信息

Department of Tumor Immunology, Polish Academy of Sciences, Wrocław.

出版信息

Arch Immunol Ther Exp (Warsz). 1989;37(5-6):547-56.

PMID:2487366
Abstract

The alkylating agent ifosfamide synthesized according to own method at the Institute of Pharmaceutical Industry, Warsaw, was compared in biological evaluations with Holoxan (Asta-Werke's ifosfamide). No significant differences between tested compounds were found in respect of acute toxicity and antitumor activity in experimental systems in mice.

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