PET/CT 检查在一例 FDG 摄取的弥漫性泪腺 MALT 瘤患者中的发现，该患者随后发展为大 B 细胞淋巴瘤和胃 MALT 瘤。

PET/CT findings in a case with FDG-avid disseminated lacrimal gland MALToma with sequential development of large B-cell lymphoma and gastric MALToma.

机构信息

From the Departments of *Nuclear Medicine, †Hematology, and ‡Pathology, Ankara Ataturk Research and Training Hospital, Ankara, Turkey.

出版信息

Clin Nucl Med. 2015 Feb;40(2):141-5. doi: 10.1097/RLU.0000000000000468.

DOI:10.1097/RLU.0000000000000468

PMID:24873799

Abstract

Primary orbital lymphomas are rare; the major histopathologic type is extranodal marginal-zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) or MALToma. We present a case of a 79-year-old female patient with FDG-avid lacrimal gland MALToma with nodal and pulmonary involvement (stage IVE). Nasopharynx and gastric involvement were detected on restaging F-FDG PET/CT after rituximab therapy, and it was found to have a site of transformation to diffuse large B-cell lymphoma (DLBCL) in the nasopharynx. Gastric MALT lymphoma was also confirmed histopathologically, and she then underwent combination chemotherapy regimen, resulting in regression after 3 courses.

摘要

原发性眼眶淋巴瘤罕见，主要组织病理学类型为黏膜相关淋巴组织（MALT）结外边缘区 B 细胞淋巴瘤或 MALT 淋巴瘤。我们报告 1 例 79 岁女性患者，其 FDG 摄取的泪腺 MALT 淋巴瘤伴淋巴结和肺部累及（IV 期 E）。利妥昔单抗治疗后行 F-FDG PET/CT 分期检查发现鼻咽部和胃部受累，且在鼻咽部发现转化为弥漫性大 B 细胞淋巴瘤（DLBCL）的病灶。胃 MALT 淋巴瘤也经组织病理学证实，患者随后接受联合化疗方案治疗，3 个疗程后肿瘤消退。