用氟代脱氧葡萄糖正电子发射断层扫描（FDG-PET）研究黏膜相关淋巴组织淋巴瘤：与CT及内镜检查结果的比较
Mucosa-associated lymphoid tissue lymphoma studied with FDG-PET: a comparison with CT and endoscopic findings.
作者信息
Enomoto Keisuke, Hamada Kenichiro, Inohara Hidenori, Higuchi Ichiro, Tomita Yasuhiko, Kubo Takeshi, Hatazawa Jun
机构信息
Department of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, Japan.
出版信息
Ann Nucl Med. 2008 May;22(4):261-7. doi: 10.1007/s12149-007-0125-9. Epub 2008 Jun 6.
OBJECTIVE
We investigated the accumulation of 2-deoxy-2-[(18)F] fluoro-D: -glucose positron emission tomography (FDG-PET) in patients with mucosa-associated lymphoid tissue (MALT) lymphoma patients as compared with computerized tomography (CT) and endoscopic imaging.
METHODS
FDG-PET was performed on 13 untreated patients with MALT lymphoma. CT scanning of the affected areas was performed in all the patients to compare with the FDG-PET images. In five patients with gastric MALT lymphoma, comparison was also made with the endoscopic findings.
RESULTS
Of the 13 untreated MALT lymphoma patients, all 8 non-gastric MALT lymphoma patients exhibited abnormal accumulation of FDG. However, in the five gastric MALT lymphoma patients, no abnormal FDG accumulation was observed. Although lesions could be confirmed on CT images from the patients other than those with gastric MALT lymphoma, the mucosal lesions of gastric MALT lymphoma could be observed only by endoscopy.
CONCLUSIONS
FDG-PET can be used to detect MALT lymphoma when it forms mass lesions, whereas it is difficult to detect non-massive MALT lymphoma of gastrointestinal origin.
目的
我们研究了黏膜相关淋巴组织（MALT）淋巴瘤患者中2-脱氧-2-[(18)F]氟-D-葡萄糖正电子发射断层扫描（FDG-PET）的积聚情况，并与计算机断层扫描（CT）和内镜成像进行比较。
方法
对13例未经治疗的MALT淋巴瘤患者进行了FDG-PET检查。对所有患者进行了患区的CT扫描，以与FDG-PET图像进行比较。对5例胃MALT淋巴瘤患者，还与内镜检查结果进行了比较。
结果
在13例未经治疗的MALT淋巴瘤患者中，所有8例非胃MALT淋巴瘤患者均表现出FDG异常积聚。然而，在5例胃MALT淋巴瘤患者中，未观察到FDG异常积聚。除胃MALT淋巴瘤患者外，其他患者的病变可在CT图像上得到证实，而胃MALT淋巴瘤的黏膜病变只能通过内镜观察到。
结论
当MALT淋巴瘤形成肿块病变时，FDG-PET可用于检测，而胃肠道起源的非肿块性MALT淋巴瘤则难以检测。
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