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匹兹堡大学:在积分制下进行三年零九个月尸体肾移植的经验。

The University of Pittsburgh: a three and three-quarter-year experience with cadaveric renal transplantation under the point system.

作者信息

Shapiro R, Tzakis A G, Fung J J, Hakala T R, Jordan M L, Hickey D, Iwaki Y, Starzl T E

机构信息

Department of Surgery, University Health Center of Pittsburgh, Pennsylvania.

出版信息

Clin Transpl. 1989:287-93.

Abstract

Eight hundred and sixty kidney transplants were performed at the University of Pittsburgh over a 3.75-year period between January 1, 1986 and October 19, 1989. Recipient selection was by means of a computerized point system designed to allocate organs equitably. Ninety-three percent 1-year patient survival and 74% 1-year graft survival were obtained in the overall group; 80% 1-year graft survival was obtained in patients receiving immunosuppression with CsA, azathioprine, and prednisone. These data serve as a measure of what can be achieved with an equitably based allocation system and can serve as a basis of comparison with other allocation protocols or new immunosuppressive regimens.

摘要

1986年1月1日至1989年10月19日的3.75年期间,匹兹堡大学进行了860例肾移植手术。通过一个旨在公平分配器官的计算机化积分系统来选择受者。总体组患者1年生存率为93%,移植物1年生存率为74%;接受环孢素、硫唑嘌呤和泼尼松免疫抑制治疗的患者移植物1年生存率为80%。这些数据可衡量基于公平原则的分配系统所能取得的成效,并可作为与其他分配方案或新的免疫抑制方案进行比较的基础。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5316/2989673/648b410a9406/nihms249875f1.jpg

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