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对用于肾移植受者选择的UNOS评分系统的评估。

Evaluation of the UNOS point system for kidney recipient selection.

作者信息

McClelland J, Terasaki P I, Berne T, Brennan L P, Bretan P, Cohen A, Dainko E, Danovitch G, Ettenger R, Lieberman E

机构信息

UCLA Tissue Typing Laboratory.

出版信息

Clin Transpl. 1989:471-6.

PMID:2487616
Abstract
  1. The ultimate distribution of 479 consecutive cadaver donor kidneys in the Los Angeles area was examined to determine whether the distribution had been equitable. Half of the kidneys had been allocated by the UNOS point system (or slight modifications thereof) and half by the transplant centers according to their own criteria. 2. With respect to waiting time, the pool of 1,000 was composed of 14% patients who had waited more than 2 years. The UNOS point system forced the transplantation of more patients (27%) who had waited longer than 2 years than the nonpoint system (11%). 3. Although the waiting pool was composed of 28% waiting for retransplantation, the UNOS point system resulted in transplantation of 16% and the nonpoint system, 8%. 4. In the waiting pool, 16% of the patients had cytotoxic antibodies reactive to more than 80% of the panel, whereas 11% of the transplants by the UNOS point system were transplanted into highly sensitized patients and only 2% of the patients transplanted by the nonpoint system were highly sensitized. 5. In Los Angeles, where 11% of the population is Black, 10% of the kidneys transplanted were into Black patients. Since 18% of the waiting pool of patients were Black, some shortfall was noted. However, this can be attributed to the fact that only 7% of the donors were Black. The importance of increasing donation from the Black community is emphasized. 6. Because of the limited pool size of 1,000 patients only a small number of 0 B,DR transplants were achieved.(ABSTRACT TRUNCATED AT 250 WORDS)
摘要
  1. 对洛杉矶地区连续479例尸体供肾的最终分配情况进行了检查,以确定分配是否公平。一半的肾脏通过器官共享联合网络(UNOS)积分系统(或其轻微修改版本)进行分配,另一半则由移植中心根据自身标准分配。2. 关于等待时间,1000名患者的队列中,14%的患者等待时间超过2年。UNOS积分系统促使更多等待超过2年的患者接受移植(27%),而非积分系统的这一比例为11%。3. 尽管等待队列中有28%的患者等待再次移植,但UNOS积分系统导致16%的此类患者接受了移植,非积分系统为8%。4. 在等待队列中,16%的患者具有对超过80%的样本细胞产生反应的细胞毒性抗体,而通过UNOS积分系统进行的移植中,11%是移植给高度致敏患者,非积分系统进行移植的患者中只有2%是高度致敏的。5. 在洛杉矶,11%的人口为黑人,而接受移植的肾脏中有10%移植给了黑人患者。由于等待队列中有18%的患者是黑人,因此存在一定差距。然而,这可能归因于只有7%的供者为黑人。强调了增加黑人社区捐赠的重要性。6. 由于只有1000名患者的队列规模有限,仅完成了少量的0 B,DR移植。(摘要截短于250词)

相似文献

1
Evaluation of the UNOS point system for kidney recipient selection.对用于肾移植受者选择的UNOS评分系统的评估。
Clin Transpl. 1989:471-6.
2
Kidney allocation under the UNOS point system: an update.美国器官共享联合网络(UNOS)积分系统下的肾脏分配:最新情况
Clin Transpl. 1992:405-11.
3
Los Angeles organ sharing: twenty-six-year report.洛杉矶器官共享:26年报告。
Clin Transpl. 1993:345-9.
4
Kidney transplantation in the United States.美国的肾脏移植
Clin Transpl. 2008:1-18.
5
The UNOS scientific renal transplant registry. United Network for Organ Sharing.美国器官共享联合网络(UNOS)的科学肾脏移植登记处。
Clin Transpl. 1995:1-18.
6
The OPTN/UNOS Renal Transplant Registry.器官获取与移植网络/美国器官共享联合网络肾脏移植登记处
Clin Transpl. 2005:1-16.
7
The LifeLink Foundation and cadaver kidney transplantation in Tampa.生命链接基金会与坦帕的尸体肾移植
Clin Transpl. 1999:149-58.
8
The UNOS Renal Transplant Registry.美国器官共享联合网络肾脏移植登记处。
Clin Transpl. 2002:1-20.
9
Transplantation of A2 and A2B kidneys from deceased donors into B waiting list candidates increases their transplantation rate.将已故供体的A2和A2B肾脏移植给B类等待名单上的候选者可提高他们的移植率。
Clin Transpl. 2004:127-33.
10
The UNOS Scientific Renal Transplant Registry--ten years of kidney transplants.美国器官共享联合网络科学肾脏移植登记处——十年肾脏移植情况
Clin Transpl. 1997:1-14.

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