挽救性食管切除术
Salvage esophagectomy.
作者信息
Hofstetter Wayne L
机构信息
Department of Thoracic and Cardiovascular Surgery, University of Texas, MD Anderson Cancer Center, Houston, Texas, USA.
出版信息
J Thorac Dis. 2014 May;6 Suppl 3(Suppl 3):S341-9. doi: 10.3978/j.issn.2072-1439.2014.03.29.
Abstract
Patients with locally advanced esophageal cancer are treated with definitive chemoradiation (dCXRT) for a number of reasons. Some patients are never referred to a surgeon for a con-versation about surgery, others decline surgery, and some are not candidates for surgery due to a sag in performance status secondary to therapy. Regardless of method of arrival at dCXRT, the risk of local/regional recurrence during follow-up is significant. Many of these patients are faced with limited options for therapy once dCXRT has failed. Salvage esoph-agectomy has historically been considered a morbid procedure and poor choice for lo-cal/regional recurrence. This chapter reviews the recent literature arguing the relevance of salvage resection. We recommend that any patient suffering from persistent or recurrent lo-cal/regional only disease after dCXRT should be referred to an experienced esophageal center to consider surgical options.
摘要
局部晚期食管癌患者接受根治性放化疗（dCXRT）有多种原因。一些患者从未被转介给外科医生讨论手术事宜，另一些患者拒绝手术，还有一些患者由于治疗后身体状况下降而不适合手术。无论采用何种方式接受dCXRT，随访期间局部/区域复发的风险都很高。一旦dCXRT失败，这些患者中的许多人面临的治疗选择有限。挽救性食管切除术历来被认为是一种创伤性大的手术，对于局部/区域复发来说不是一个好的选择。本章回顾了近期关于挽救性切除相关性的文献。我们建议，任何在dCXRT后仅患有持续性或复发性局部/区域疾病的患者，都应被转介至经验丰富的食管疾病中心，以考虑手术选择。
相似文献
1
Salvage esophagectomy.挽救性食管切除术
J Thorac Dis. 2014 May;6 Suppl 3(Suppl 3):S341-9. doi: 10.3978/j.issn.2072-1439.2014.03.29.
2
Salvage esophagectomy for persistent or recurrent disease after definitive chemoradiation.对于确定性放化疗后持续或复发疾病行挽救性食管切除术。
Ann Cardiothorac Surg. 2017 Mar;6(2):144-151. doi: 10.21037/acs.2017.03.02.
3
Salvage or planned esophagectomy after chemoradiation therapy for locally advanced esophageal cancer--a review.局部晚期食管癌放化疗后挽救性或计划性食管切除术——综述
Dis Esophagus. 2003;16(2):60-5. doi: 10.1046/j.1442-2050.2003.00296.x.
4
[Techniques for Preventing Postoperative Complication in Esophageal Salvage Surgery].
Kyobu Geka. 2017 Jul;70(8):720-727.
5
Salvage esophagectomy after failed definitive chemoradiation for esophageal adenocarcinoma.根治性放化疗失败后的食管腺癌挽救性切除术。
Ann Thorac Surg. 2012 Oct;94(4):1126-32; discussion 1132-3. doi: 10.1016/j.athoracsur.2012.05.106. Epub 2012 Aug 24.
6
Treatment of locally advanced esophageal cancer with surgery and chemoradiation.采用手术及放化疗治疗局部晚期食管癌。
Curr Opin Gastroenterol. 2008 Jul;24(4):535-40. doi: 10.1097/MOG.0b013e3283025ca2.
7
A meta-analysis on salvage surgery as a potentially curative procedure in patients with isolated local recurrent or persistent esophageal cancer after chemoradiotherapy.一项关于挽救性手术作为局部复发或持续性食管癌患者在放化疗后潜在治愈手段的荟萃分析。
Eur J Surg Oncol. 2019 Jun;45(6):931-940. doi: 10.1016/j.ejso.2018.11.002. Epub 2018 Nov 10.
8
A Phase II study of a paclitaxel-based chemoradiation regimen with selective surgical salvage for resectable locoregionally advanced esophageal cancer: initial reporting of RTOG 0246.一项基于紫杉醇的放化疗方案联合选择性手术挽救治疗可切除局部晚期食管癌的 II 期研究：RTOG 0246 的初步报告。
Int J Radiat Oncol Biol Phys. 2012 Apr 1;82(5):1967-72. doi: 10.1016/j.ijrobp.2011.01.043. Epub 2011 Apr 18.
9
Comparison of salvage chemoradiation versus salvage surgery for recurrent esophageal squamous cell carcinoma after definitive radiochemotherapy or radiotherapy alone.根治性放化疗或单纯放疗后复发的食管鳞癌行挽救性放化疗与挽救性手术的比较。
Dis Esophagus. 2014 Feb-Mar;27(2):134-40. doi: 10.1111/j.1442-2050.2012.01440.x. Epub 2012 Oct 22.
10
Surgical salvage therapy: abdominoperineal resection for recurrent anal carcinoma, metastasectomy of recurrent colorectal cancer, and esophagectomy after combined chemoradiation.手术挽救性治疗：复发性肛管癌的腹会阴联合切除术、复发性结直肠癌的转移灶切除术以及放化疗联合后的食管切除术。
Curr Opin Oncol. 2000 Jul;12(4):353-6. doi: 10.1097/00001622-200007000-00012.
引用本文的文献
1
International Expert Consensus on Semantics of Multimodal Esophageal Cancer Treatment: Delphi Study.国际多模态食管癌治疗语义共识专家：德尔菲研究。
Ann Surg Oncol. 2024 Aug;31(8):5075-5082. doi: 10.1245/s10434-024-15367-w. Epub 2024 May 8.
2
Salvage minimally invasive esophagectomy after definitive chemoradiotherapy for esophageal cancer can improve postoperative complications compared with salvage open esophagectomy.与挽救性开放食管切除术相比，食管癌根治性放化疗后行挽救性微创食管切除术可改善术后并发症。
Surg Endosc. 2022 May;36(5):3504-3510. doi: 10.1007/s00464-021-08672-y. Epub 2021 Oct 12.
3
It's not always too late: a case for minimally invasive salvage esophagectomy.并非总是为时过晚：微创挽救性食管切除术 1 例报告。
Surg Endosc. 2021 Aug;35(8):4700-4711. doi: 10.1007/s00464-020-07937-2. Epub 2020 Sep 17.
4
Definitive chemoradiotherapy versus neoadjuvant chemoradiotherapy followed by surgery for stage II to III esophageal squamous cell carcinoma.根治性放化疗对比新辅助放化疗后手术治疗 II 期到 III 期食管鳞癌。
J Thorac Cardiovasc Surg. 2018 Jun;155(6):2710-2721.e3. doi: 10.1016/j.jtcvs.2018.01.086. Epub 2018 Feb 15.
5
Long-term survival and toxicity outcomes of intensity modulated radiation therapy for the treatment of esophageal cancer: A large single-institutional cohort study.调强放射治疗食管癌的长期生存及毒性结果：一项大型单机构队列研究
Adv Radiat Oncol. 2017 Apr 19;2(3):316-324. doi: 10.1016/j.adro.2017.04.002. eCollection 2017 Jul-Sep.
6
[Salvage surgery in esophageal cancer : Feasibility in patients after definitive radiochemotherapy (> 50 Gy)].[食管癌挽救性手术：根治性放化疗（>50 Gy）后患者的可行性]
Chirurg. 2015 Oct;86(10):955-62. doi: 10.1007/s00104-014-2971-z.
本文引用的文献
1
Influence of preoperative radiation field on postoperative leak rates in esophageal cancer patients after trimodality therapy.术前放疗野对食管癌患者三联疗法术后漏率的影响。
J Thorac Oncol. 2014 Apr;9(4):534-40. doi: 10.1097/JTO.0000000000000100.
2
Factors associated with local-regional failure after definitive chemoradiation for locally advanced esophageal cancer.局部晚期食管癌根治性放化疗后与局部区域失败相关的因素。
Ann Surg Oncol. 2014 Jan;21(1):306-14. doi: 10.1245/s10434-013-3303-0. Epub 2013 Nov 7.
3
Surgery is an essential component of multimodality therapy for patients with locally advanced esophageal adenocarcinoma.手术是局部晚期食管腺癌患者多模式治疗的重要组成部分。
J Gastrointest Surg. 2013 Aug;17(8):1359-69. doi: 10.1007/s11605-013-2223-4. Epub 2013 May 29.
4
Omental reinforcement of the thoracic esophagogastric anastomosis: an analysis of leak and reintervention rates in patients undergoing planned and salvage esophagectomy.网膜加强胸内食管胃吻合术：计划性和抢救性食管切除术患者吻合口漏和再次干预率的分析。
J Thorac Cardiovasc Surg. 2012 Nov;144(5):1146-50. doi: 10.1016/j.jtcvs.2012.07.085. Epub 2012 Aug 28.
5
Salvage esophagectomy after failed definitive chemoradiation for esophageal adenocarcinoma.根治性放化疗失败后的食管腺癌挽救性切除术。
Ann Thorac Surg. 2012 Oct;94(4):1126-32; discussion 1132-3. doi: 10.1016/j.athoracsur.2012.05.106. Epub 2012 Aug 24.
6
Esophageal and esophagogastric junction cancers.食管癌和食管胃交界癌。
J Natl Compr Canc Netw. 2011 Aug 1;9(8):830-87. doi: 10.6004/jnccn.2011.0072.
7
A Phase II study of a paclitaxel-based chemoradiation regimen with selective surgical salvage for resectable locoregionally advanced esophageal cancer: initial reporting of RTOG 0246.一项基于紫杉醇的放化疗方案联合选择性手术挽救治疗可切除局部晚期食管癌的 II 期研究：RTOG 0246 的初步报告。
Int J Radiat Oncol Biol Phys. 2012 Apr 1;82(5):1967-72. doi: 10.1016/j.ijrobp.2011.01.043. Epub 2011 Apr 18.
8
Stage-for-stage comparison of definitive chemoradiotherapy, surgery alone and neoadjuvant chemotherapy for oesophageal carcinoma.食管癌根治性放化疗、单纯手术及新辅助化疗的逐阶段比较。
Br J Surg. 2009 Nov;96(11):1300-7. doi: 10.1002/bjs.6705.
9
Prospective comparison of surgery alone and chemoradiotherapy with selective surgery in resectable squamous cell carcinoma of the esophagus.可切除食管鳞状细胞癌单纯手术与放化疗联合选择性手术的前瞻性比较。
Int J Radiat Oncol Biol Phys. 2009 Oct 1;75(2):348-56. doi: 10.1016/j.ijrobp.2009.02.086.
10
Salvage esophagectomy after high-dose chemoradiotherapy for esophageal squamous cell carcinoma.食管鳞状细胞癌大剂量放化疗后的挽救性食管切除术
J Thorac Cardiovasc Surg. 2009 Jan;137(1):49-54. doi: 10.1016/j.jtcvs.2008.05.016.
Zotero 插件