Galceran T E, Vázquez M C, Martín R S, Firmat J, Arrizurieta E
Medicina (B Aires). 1989;49(4):325-30.
Ten patients with acute renal failure post-septic abortion were studied. Two groups of patients are described in terms of duration of oliguria, number of dialysis per patient and maximal concentration of BUN during the acute episode of tubular necrosis. Despite different oliguric periods, when the patients reached 500 ml of urine volume in 24 hours, the recovery of diuresis was similar in both groups as well as the decrease of BUN concentration at the end of the hemodialysis period. Functional studies were carried out, up to an average of 10.5 years after the acute episode. Mean values for inulin and para-aminohippurate clearances were 107 +/- 11.53 and 534.6 +/- 62.9 ml/min./1.73 m2 in nonoliguric patients or those with a short period of oliguria. These values are not significantly different from the mean values of Wesson for normal women. On the other hand, reductions in both clearances were present in most patients who had a long period of oliguria (GFR: 84.9 +/- 4.2 and RPF: 418.1 +/- 33.1). These results demonstrate that the duration of oliguria at the time acute renal failure occurred is the most important factor influencing the rate and extent of long-term recovery of renal function.
对10例感染性流产后急性肾衰竭患者进行了研究。根据少尿持续时间、每位患者的透析次数以及肾小管坏死急性期血尿素氮的最高浓度,对两组患者进行了描述。尽管少尿期不同,但当患者24小时尿量达到500毫升时,两组患者的利尿恢复情况相似,血液透析期末血尿素氮浓度的下降情况也相似。在急性期后平均长达10.5年进行了功能研究。非少尿患者或少尿期短的患者中,菊粉清除率和对氨基马尿酸清除率的平均值分别为107±11.53和534.6±62.9毫升/分钟/1.73平方米。这些值与正常女性的韦森平均值无显著差异。另一方面,大多数少尿期长的患者(肾小球滤过率:84.9±4.2,肾血浆流量:418.1±33.1)的清除率均降低。这些结果表明,急性肾衰竭发生时少尿的持续时间是影响肾功能长期恢复速度和程度的最重要因素。