Krause Sandra, Rydall Anne, Hales Sarah, Rodin Gary, Lo Chris
Department of Psychosocial Oncology and Palliative Care, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
Department of Psychosocial Oncology and Palliative Care, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
J Pain Symptom Manage. 2015 Jan;49(1):126-34. doi: 10.1016/j.jpainsymman.2014.04.012. Epub 2014 May 28.
The experience of death anxiety in patients with advanced cancer has been understudied partly because of the lack of a tailored measure for this population. The Death and Dying Distress Scale (DADDS) was constructed to address this gap. Although an initial version of this instrument has shown promising psychometric properties, validation of the finalized version is needed.
This study aims to validate the recent 15-item DADDS by examining its factor structure and construct validity.
Sixty participants with advanced or metastatic cancer were recruited from the Princess Margaret Cancer Centre, University Health Network, Toronto, Canada, into a pilot trial of a psychological intervention. This article analyzes the baseline measures on death anxiety, depressive symptoms (Patient Health Questionnaire-9, Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision, Axis 1 Disorders), generalized anxiety (Generalized Anxiety Disorder-7), and preparation for end of life (Quality of Life at the End of Life-Cancer Scale). Exploratory factor analysis was conducted. Construct validity was assessed by correlations between measures.
Factor analysis revealed a dominant single factor explaining more than 75% of the shared variation between items. Factor loadings were high, ranging from 0.57 to 0.86. Item communalities were evenly ranged from 0.33 to 0.75 and with the 15:1 variable to factor ratio, suggest the viability of parameter estimates despite the small sample size. Cronbach's alpha was 0.95. Death anxiety was associated with less preparation for end of life (r = -0.68, P < 0.0001), more generalized anxiety (r = 0.63, P < 0.0001), and more depressive symptom severity (r = 0.50, P < 0.0001). Individuals with major depression had greater death anxiety than the nondepressed (mean difference = 17; 95% CI = 1.5-33), as did individuals with minor depression (mean difference = 25; 95% CI = 10-41).
The DADDS is a valid measure of death anxiety in patients with advanced cancer. It may provide useful information in the assessment and treatment of distress in patients near the end of life.
晚期癌症患者的死亡焦虑体验尚未得到充分研究,部分原因是缺乏针对该人群的特定测量工具。死亡与濒死困扰量表(DADDS)就是为填补这一空白而构建的。尽管该工具的初始版本已显示出良好的心理测量特性,但仍需要对最终版本进行验证。
本研究旨在通过检验其因子结构和结构效度来验证最新的15项DADDS。
从加拿大多伦多大学健康网络玛格丽特公主癌症中心招募了60名晚期或转移性癌症患者,参与一项心理干预的试点试验。本文分析了关于死亡焦虑、抑郁症状(患者健康问卷-9,精神障碍诊断与统计手册第四版,文本修订版,轴I障碍的结构化临床访谈)、广泛性焦虑(广泛性焦虑障碍-7)以及临终准备(临终生活质量-癌症量表)的基线测量数据。进行了探索性因子分析。通过各测量指标之间的相关性评估结构效度。
因子分析揭示了一个主导的单一因子,解释了项目间超过75%的共同变异。因子载荷较高,范围从0.57至0.86。项目共同度均匀地分布在0.33至0.75之间,且变量与因子比例为15:1,这表明尽管样本量较小,但参数估计仍具有可行性。克朗巴哈系数为0.95。死亡焦虑与较少的临终准备相关(r = -0.68,P < 0.0001),与更多的广泛性焦虑相关(r = 0.63,P < 0.0001),以及与更严重的抑郁症状相关(r = 0.50,P < 0.0001)。患有重度抑郁症的个体比未患抑郁症的个体有更高的死亡焦虑(平均差异 = 17;95%可信区间 = 1.5 - 33),轻度抑郁症患者也是如此(平均差异 = 25;95%可信区间 = 10 - 41)。
DADDS是晚期癌症患者死亡焦虑的有效测量工具。它可能为临终患者困扰的评估和治疗提供有用信息。