Laboratoire Interactions Plantes Micro-organismes (LIPM) UMR441/2594, INRA/CNRS, F-31320 and INRA, Unité de Mathématiques et Informatique Appliques de Toulouse, UR 875, Castanet-Tolosan F-31326, France.
Bioinformatics. 2014 Sep 15;30(18):2659-61. doi: 10.1093/bioinformatics/btu366. Epub 2014 May 30.
It is now easy and increasingly usual to produce oriented RNA-Seq data as a prokaryotic genome is being sequenced. However, this information is usually just used for expression quantification. EuGene-PP is a fully automated pipeline for structural annotation of prokaryotic genomes integrating protein similarities, statistical information and any oriented expression information (RNA-Seq or tiling arrays) through a variety of file formats to produce a qualitatively enriched annotation including coding regions but also (possibly antisense) non-coding genes and transcription start sites.
EuGene-PP is an open-source software based on EuGene-P integrating a Galaxy configuration. EuGene-PP can be downloaded at eugene.toulouse.inra.fr.
现在，随着原核基因组测序变得越来越容易和常见，产生定向 RNA-Seq 数据也变得越来越容易。然而，这些信息通常仅用于表达定量。EuGene-PP 是一个完全自动化的原核基因组结构注释流水线，它通过各种文件格式整合蛋白质相似性、统计信息和任何定向表达信息（RNA-Seq 或平铺阵列），生成一个定性丰富的注释，包括编码区域，但也包括（可能是反义的）非编码基因和转录起始位点。
EuGene-PP 是一个基于 EuGene-P 的开源软件，集成了 Galaxy 配置。EuGene-PP 可以在 eugene.toulouse.inra.fr 下载。
