Carrión Silvia, Cabré Mateu, Monteis Rosa, Roca Maria, Palomera Elisabet, Serra-Prat Mateu, Rofes Laia, Clavé Pere
GI Physiology Laboratory, Department of Surgery, Hospital de Mataró, Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (Ciberehd), Instituto de Salud Carlos III, Barcelona, Spain.
Department of Internal Medicine, Hospital de Mataró, Barcelona, Spain.
Clin Nutr. 2015 Jun;34(3):436-42. doi: 10.1016/j.clnu.2014.04.014. Epub 2014 May 9.
BACKGROUND & AIMS: Oropharyngeal dysphagia and malnutrition are prevalent conditions in the older. The aim of this study was to explore the relationship between oropharyngeal dysphagia, nutritional status and clinical outcome in older patients admitted to an acute geriatric unit.
We studied 1662 patients ≥70 years consecutively hospitalized with acute diseases, in whom dysphagia could be clinically assessed by the volume-viscosity swallow test and nutritional status with the Mini Nutritional Assessment(®). Anthropometric and laboratory measurements were taken and mortality recorded during hospital stay, at 6 months and one year after discharge was recorded.
47.4% (95% CI 45-49.8%) patients presented oropharyngeal dysphagia and 30.6% (95% CI 27.9%-33.3%), malnutrition. Both conditions were associated with multimorbidity, multiple geriatric syndromes and poor functional capacity (p < 0.001). However, patients with dysphagia presented increased prevalence of malnutrition (MNA(®) < 17 45.3% vs 18%, p < 0.001) regardless of their functional status and comorbidities (OR 2.31 (1.70-3.14)) and lower albumin and cholesterol levels. Patients with malnutrition presented an increased prevalence of dysphagia (68.4% (95% CI 63.3-73.4)). Patients with dysphagia and patients with malnutrition presented increased intrahospital, 6-month and 1-year mortality rates (p < 0.05). The poorest outcome was for patients with both conditions (1-year mortality was 65.8%).
Prevalence of dysphagia was higher than malnutrition in our older patients. Dysphagia was an independent risk factor for malnutrition, and both conditions were related to poor outcome.
口咽吞咽困难和营养不良在老年人中普遍存在。本研究旨在探讨入住急性老年病科的老年患者口咽吞咽困难、营养状况与临床结局之间的关系。
我们连续研究了1662例≥70岁因急性疾病住院的患者,通过容量 - 粘度吞咽试验对其吞咽困难进行临床评估,并使用微型营养评定法(Mini Nutritional Assessment(®))评估营养状况。进行人体测量和实验室检测,并记录住院期间、出院后6个月和1年的死亡率。
47.4%(95%可信区间45 - 49.8%)的患者存在口咽吞咽困难,30.6%(95%可信区间27.9% - 33.3%)存在营养不良。这两种情况均与多种疾病、多种老年综合征及功能能力差相关(p < 0.001)。然而,无论功能状态和合并症如何,吞咽困难患者的营养不良患病率均较高(微型营养评定法(MNA(®))< 17分,45.3%对18%,p < 0.001),且白蛋白和胆固醇水平较低。营养不良患者的吞咽困难患病率较高(68.4%(95%可信区间63.3 - 73.4))。吞咽困难患者和营养不良患者的院内、6个月和1年死亡率均升高(p < 0.05)。两种情况并存的患者结局最差(1年死亡率为65.8%)。
在我们的老年患者中,吞咽困难的患病率高于营养不良。吞咽困难是营养不良的独立危险因素,且这两种情况均与不良结局相关。