Dini Francesca, Mancini Stefania, Girelli Alessia, Ercolini Daniela Perelli, Reggiani Alessandro, Alonso Yanely Sarduy, Inzitari Marco, Bellelli Giuseppe, Marengoni Alessandra, Gentile Simona, Morandi Alessandro
Intermediate Care and Rehabilitation, Azienda Speciale "Cremona Solidale", Cremona, Italy.
REFiT Bcn research group, Vall d'Hebron Institute of Research (VHIR) and Parc Sanitari Pere Virgili, Barcelona, Catalonia, Spain.
Aging Clin Exp Res. 2025 Mar 17;37(1):89. doi: 10.1007/s40520-025-02950-8.
Dysphagia is a geriatric syndrome often unrecognized or underestimated, and there is a lack of studies in a heterogeneous population in intermediate care (IC) services. This study aims to describe the prevalence of dysphagia and its association with geriatric syndromes in older patients in IC.
Prospective cohort study of patients 70 years and older admitted to an IC unit. At admission, the severity of the clinical conditions, comorbidity, delirium, frailty, sarcopenia, nutritional status, and medications were assessed. Each patient was evaluated with the 3-OZ test, and dysphagia was confirmed by a speech therapy consultation. Two multivariable logistic regression models were used to evaluate the association of dysphagia at admission with geriatric syndromes (model 1), along with the severity of illness and admission diagnosis (model 2).
A total of 455 patients were included. The prevalence of dysphagia was 10% and there was a high prevalence of mild-moderate dysphagia in patients with cognitive impairment and moderate risk of malnutrition. In the univariate analysis, an association was found between dysphagia and sarcopenia, malnutrition, and use of antipsychotics. In Model 1, higher odds of dysphagia were associated with the severity of comorbidity (Odds Ratio 6.49, 95% Confidence Interval: 2.02-20.78), and cognitive impairment (OR 0.91, 95% CI: 0.88-10.62); in Model 2, the severity of clinical conditions-NEWS2 (OR 1.61, 95% CI: 1.23-2.13) was associated with dysphagia, besides the severity of comorbidity and cognitive impairment. In a subset of 300 patients, delirium was also associated with dysphagia.
The study provides novel information on dysphagia prevalence in patients admitted to an IC unit and its association with geriatric syndromes. Additional research is needed to further define the relationship between geriatric syndromes and dysphagia, and to adequately standardize speech therapist treatments.
吞咽困难是一种常未被识别或低估的老年综合征,且针对中级护理(IC)服务中异质性人群的研究匮乏。本研究旨在描述IC中老年患者吞咽困难的患病率及其与老年综合征的关联。
对入住IC病房的70岁及以上患者进行前瞻性队列研究。入院时,评估临床病情严重程度、合并症、谵妄、衰弱、肌少症、营养状况及用药情况。每位患者均接受3-OZ测试评估,吞咽困难经言语治疗会诊确诊。使用两个多变量逻辑回归模型评估入院时吞咽困难与老年综合征的关联(模型1),以及疾病严重程度和入院诊断(模型2)。
共纳入455例患者。吞咽困难的患病率为10%,认知障碍和中度营养不良风险患者中轻至中度吞咽困难的患病率较高。单变量分析发现,吞咽困难与肌少症、营养不良及抗精神病药物使用之间存在关联。在模型1中,吞咽困难几率较高与合并症严重程度(优势比6.49,95%置信区间:2.02 - 20.78)及认知障碍(优势比0.91,95%置信区间:0.88 - 10.62)相关;在模型2中,除合并症严重程度和认知障碍外,临床病情严重程度 - NEWS2(优势比1.61,95%置信区间:1.23 - 2.13)与吞咽困难相关。在300例患者的亚组中,谵妄也与吞咽困难相关。
本研究提供了关于入住IC病房患者吞咽困难患病率及其与老年综合征关联的新信息。需要进一步研究以进一步明确老年综合征与吞咽困难之间的关系,并充分规范言语治疗师的治疗。