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胸骨伤口感染重建手术后并发症的危险因素。

Risk factors for complications after reconstructive surgery for sternal wound infection.

作者信息

Hashimoto Ichiro, Takaku Mitsuru, Matsuo Shinji, Abe Yoshiro, Harada Hiroshi, Nagae Hiroaki, Fujioka Yusuke, Anraku Kuniaki, Inagawa Kiichi, Nakanishi Hideki

机构信息

Department of Plastic and Reconstructive Surgery, The University of Tokushima Graduate School, Tokushima, Japan.

Division of Plastic Surgery, Kochi Health Sciences Center, Kochi, Japan.

出版信息

Arch Plast Surg. 2014 May;41(3):253-7. doi: 10.5999/aps.2014.41.3.253. Epub 2014 May 12.

Abstract

BACKGROUND

Although the utility of flaps for the treatment of sternal wound infections following median sternotomy has been reported for 30 years, there have been few reports on the risk factors for complications after reconstruction. The objective of this investigation was to identify factors related to complications after the reconstruction of sternal wound infections.

METHODS

A retrospective analysis of 74 patients with reconstructive surgery after sternal wound infection over a 5-year period was performed. Clinical data including age, sex, body mass index (BMI), comorbidities, bacterial culture, previous cardiac surgery, wound depth, mortality rate, type of reconstructive procedure, and complication rate were collected.

RESULTS

The patients' BMI ranged from 15.2 to 33.6 kg/m(2) (mean, 23.1±3.74 kg/m(2)). Wound closure complications after reconstructive surgery were observed in 36.5% of the cases. The mortality rate was 2.7%. Diabetes mellitus significantly affected the rate of wound closure complications (P=0.041). A significant difference in the number of complications was seen between Staphylococcus aureus (S. aureus) and coagulase-negative Staphylococci (P=0.011). There was a correlation between harvesting of the internal thoracic artery and postoperative complications (P=0.048). The complication rates of the pectoralis major flap, rectus abdominis flap, omentum flap, a combination of pectoralis major flap and rectus abdominis flap, and direct closure were 23.3%, 33.3%, 100%, 37.5%, and 35.7%, respectively.

CONCLUSIONS

Diabetes mellitus, S. aureus, harvesting of the internal thoracic artery, and omentum flap were significant factors for complications after reconstruction. The omentum flap volume may be related to the complications associated with the omentum flap transfer in the present study.

摘要

背景

尽管皮瓣用于治疗正中开胸术后胸骨伤口感染已有30年的报道,但关于重建术后并发症危险因素的报道却很少。本研究的目的是确定与胸骨伤口感染重建术后并发症相关的因素。

方法

对74例胸骨伤口感染后进行重建手术的患者进行了为期5年的回顾性分析。收集了包括年龄、性别、体重指数(BMI)、合并症、细菌培养、既往心脏手术、伤口深度、死亡率、重建手术类型和并发症发生率等临床数据。

结果

患者的BMI范围为15.2至33.6kg/m²(平均23.1±3.74kg/m²)。重建手术后伤口闭合并发症发生率为36.5%。死亡率为2.7%。糖尿病显著影响伤口闭合并发症发生率(P = 0.041)。金黄色葡萄球菌(S. aureus)和凝固酶阴性葡萄球菌之间的并发症数量存在显著差异(P = 0.011)。胸廓内动脉的采集与术后并发症之间存在相关性(P = 0.048)。胸大肌皮瓣、腹直肌皮瓣、大网膜皮瓣、胸大肌皮瓣和腹直肌皮瓣联合应用以及直接缝合的并发症发生率分别为23.3%、33.3%、100%、37.5%和35.7%。

结论

糖尿病、金黄色葡萄球菌、胸廓内动脉的采集和大网膜皮瓣是重建术后并发症的重要因素。在本研究中,大网膜皮瓣的体积可能与大网膜皮瓣转移相关的并发症有关。

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本文引用的文献

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Significant predictors of complications after sternal wound reconstruction: a 21-year experience.
Ann Plast Surg. 2012 Oct;69(4):439-41. doi: 10.1097/SAP.0b013e318231d1ef.
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