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心脏手术后因深部胸骨伤口感染行根治性胸骨切除术后的二期大网膜和胸大肌双瓣重建术。

Secondary omental and pectoralis major double flap reconstruction following aggressive sternectomy for deep sternal wound infections after cardiac surgery.

作者信息

Kobayashi Toshiro, Mikamo Akihito, Kurazumi Hiroshi, Suzuki Ryo, Shirasawa Bungo, Hamano Kimikazu

机构信息

Department of Surgery, Division of Cardiac Surgery, Yamaguchi University, Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube, Yamaguchi, 755-8505 Japan.

出版信息

J Cardiothorac Surg. 2011 Apr 18;6:56. doi: 10.1186/1749-8090-6-56.

Abstract

BACKGROUND

Deep sternal wound infection after cardiac surgery carries high morbidity and mortality. Our strategy for deep sternal wound infection is aggressive strenal debridement followed by vacuum-assisted closure (VAC) therapy and omental-muscle flap reconstrucion. We describe this strategy and examine the outcome and long-term quality of life (QOL) it achieves.

METHODS

We retrospectively examined 16 patients treated for deep sternal wound infection between 2001 and 2007. The most recent nine patients were treated with total sternal resection followed by VAC therapy and secondary closure with omental-muscle flap reconstruction (recent group); whereas the former seven patients were treated with sternal preservation if possible, without VAC therapy, and four of these patients underwent primary closure (former group). We assessed long-term quality of life after DSWI by using the Short Form 36-Item Health Survey, Version 2 (SF36v2).

RESULTS

One patient died and four required further surgery for recurrence of deep sternal wound infection in the former group. The duration of treatment for deep sternal wound infection in the recent group was significantly shorter than that in previous group (63.4 ± 54.1 days vs. 120.0 ± 31.8 days, respectively; p = 0.039). Despite aggressive sternal resection, the QOL of patients treated for DSWI was only minimally compromised compared with age-, sex-, surgical procedures-matched patients without deep sternal wound infection.

CONCLUSIONS

Aggressive sternal debridement followed by VAC therapy and secondary closure with an omental-muscle flap is effective for deep sternal wound infection. In this series, it resulted in a lower incidence of recurrent infection, shorter hospitalization, and it did not compromise long-term QOL greatly.

摘要

背景

心脏手术后深部胸骨伤口感染的发病率和死亡率都很高。我们针对深部胸骨伤口感染的策略是积极进行胸骨清创,随后采用负压封闭引流(VAC)疗法和网膜肌瓣重建术。我们描述了这一策略,并研究了其取得的结果和长期生活质量(QOL)。

方法

我们回顾性研究了2001年至2007年间接受深部胸骨伤口感染治疗的16例患者。最近的9例患者接受了全胸骨切除,随后进行VAC疗法,并采用网膜肌瓣重建术进行二期缝合(近期组);而前7例患者尽可能保留胸骨,未采用VAC疗法,其中4例患者进行了一期缝合(先前组)。我们使用简明健康调查问卷第2版(SF36v2)评估了深部胸骨伤口感染后的长期生活质量。

结果

先前组中有1例患者死亡,4例因深部胸骨伤口感染复发需要进一步手术。近期组深部胸骨伤口感染的治疗时间明显短于先前组(分别为63.4±54.1天和120.0±31.8天;p = 0.039)。尽管进行了积极的胸骨切除,但与年龄、性别、手术方式相匹配的无深部胸骨伤口感染的患者相比,接受深部胸骨伤口感染治疗的患者的生活质量仅受到轻微影响。

结论

积极进行胸骨清创,随后采用VAC疗法并使用网膜肌瓣进行二期缝合,对深部胸骨伤口感染有效。在本系列研究中,该方法导致感染复发率较低、住院时间较短,且对长期生活质量影响不大。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/16d0/3094378/4533fe592fa3/1749-8090-6-56-1.jpg

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