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Are antidepressants clinically useful? Conclusion of a decade of debate.抗抑郁药在临床上有用吗?十年辩论的结论。
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The media and intellectuals' response to medical publications: the antidepressants' case.媒体和知识分子对医学出版物的反应:抗抑郁药案例。
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Neither serotonin disorder is at the core of depression nor dopamine at the core of schizophrenia; still these are biologically based mental disorders.血清素紊乱并非抑郁症的核心,多巴胺紊乱也不是精神分裂症的核心;但这些仍是基于生物学的精神障碍。
Mol Psychiatry. 2024 Jan;29(1):198-199. doi: 10.1038/s41380-024-02458-z. Epub 2024 Feb 19.
2
Use of Quantile Treatment Effects Analysis to Describe Antidepressant Response in Randomized Clinical Trials Submitted to the US Food and Drug Administration: A Secondary Analysis of Pooled Trial Data.利用分位数治疗效果分析描述向美国食品和药物管理局提交的随机临床试验中的抗抑郁反应:汇总试验数据的二次分析。
JAMA Netw Open. 2023 Jun 1;6(6):e2317714. doi: 10.1001/jamanetworkopen.2023.17714.
3
WPA Scientific Sections: update on the activities.世界精神病学协会科学分会:活动最新情况
World Psychiatry. 2016 Jun;15(2):191-2. doi: 10.1002/wps.20317.
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EPA guidance on improving the image of psychiatry.美国环境保护局(EPA)关于改善精神病学形象的指南。
Eur Arch Psychiatry Clin Neurosci. 2016 Mar;266(2):139-54. doi: 10.1007/s00406-016-0678-5. Epub 2016 Feb 13.
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An update on the activities of WPA scientific sections.世界精神病学协会科学分会活动更新
World Psychiatry. 2015 Jun;14(2):255-6. doi: 10.1002/wps.20226.

本文引用的文献

1
Burning issues in the meta-analysis of pharmaceutical trials for depression.药物治疗抑郁症临床试验的荟萃分析中的热点问题。
J Psychopharmacol. 2014 Feb;28(2):106-17. doi: 10.1177/0269881113504014. Epub 2013 Sep 16.
2
No role for initial severity on the efficacy of antidepressants: results of a multi-meta-analysis.抗抑郁药疗效与初始严重程度无关:一项多荟萃分析的结果。
Ann Gen Psychiatry. 2013 Aug 13;12(1):26. doi: 10.1186/1744-859X-12-26.
3
The media and intellectuals' response to medical publications: the antidepressants' case.媒体和知识分子对医学出版物的反应:抗抑郁药案例。
Ann Gen Psychiatry. 2013 Apr 12;12(1):11. doi: 10.1186/1744-859X-12-11.
4
A systematic review of comparative efficacy of treatments and controls for depression.系统评价抑郁症治疗和对照措施的疗效比较。
PLoS One. 2012;7(7):e41778. doi: 10.1371/journal.pone.0041778. Epub 2012 Jul 30.
5
Putting the efficacy of psychiatric and general medicine medication into perspective: review of meta-analyses.从精神病学和一般医学药物疗效的角度来看:荟萃分析综述。
Br J Psychiatry. 2012 Feb;200(2):97-106. doi: 10.1192/bjp.bp.111.096594.
6
Randomized, placebo-controlled trials of antidepressants for acute major depression: thirty-year meta-analytic review.抗抑郁药治疗急性重度抑郁症的随机、安慰剂对照试验:三十年的荟萃分析回顾。
Neuropsychopharmacology. 2012 Mar;37(4):851-64. doi: 10.1038/npp.2011.306. Epub 2011 Dec 14.
7
Comparative efficacy and acceptability of mood stabilizer and second generation antipsychotic monotherapy for acute mania--a systematic review and meta-analysis.心境稳定剂与第二代抗精神病药单药治疗急性躁狂症的疗效和可接受性比较——系统评价和荟萃分析。
J Affect Disord. 2011 Nov;134(1-3):14-9. doi: 10.1016/j.jad.2010.11.009. Epub 2010 Dec 9.
8
Efficacy of antimanic treatments: meta-analysis of randomized, controlled trials.抗躁狂治疗的疗效:随机对照试验的荟萃分析。
Neuropsychopharmacology. 2011 Jan;36(2):375-89. doi: 10.1038/npp.2010.192. Epub 2010 Oct 27.
9
Efficacy of antidepressants: a re-analysis and re-interpretation of the Kirsch data.抗抑郁药的疗效:对 Kirsch 数据的再分析和再解释。
Int J Neuropsychopharmacol. 2011 Apr;14(3):405-12. doi: 10.1017/S1461145710000957. Epub 2010 Aug 27.
10
Placebo, prozac and PLoS: significant lessons for psychopharmacology.安慰剂、百忧解和 PLoS:精神药理学的重要教训。
J Psychopharmacol. 2011 Oct;25(10):1277-88. doi: 10.1177/0269881110372544. Epub 2010 Jun 22.

Are antidepressants clinically useful? Conclusion of a decade of debate.

作者信息

Fountoulakis Konstantinos N, Möller Hans-Jürgen

机构信息

3rd Department of Psychiatry, School of Medicine, Aristotle University of Thessaloniki, Greece.

出版信息

World Psychiatry. 2014 Jun;13(2):201-2. doi: 10.1002/wps.20112.

DOI:10.1002/wps.20112
PMID:24890076
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4102296/
Abstract
摘要