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Neither serotonin disorder is at the core of depression nor dopamine at the core of schizophrenia; still these are biologically based mental disorders.

作者信息

Fountoulakis Konstantinos N, Tsapakis Eva Maria

机构信息

3rd Department of Psychiatry, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece.

"Agios Charalambos" Mental Health Clinic, Heraklion, Crete, Greece.

出版信息

Mol Psychiatry. 2024 Jan;29(1):198-199. doi: 10.1038/s41380-024-02458-z. Epub 2024 Feb 19.

DOI:10.1038/s41380-024-02458-z
PMID:38374355
Abstract
摘要

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1
Neither serotonin disorder is at the core of depression nor dopamine at the core of schizophrenia; still these are biologically based mental disorders.血清素紊乱并非抑郁症的核心，多巴胺紊乱也不是精神分裂症的核心；但这些仍是基于生物学的精神障碍。
Mol Psychiatry. 2024 Jan;29(1):198-199. doi: 10.1038/s41380-024-02458-z. Epub 2024 Feb 19.
2
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Nat Rev Neurosci. 2016 Aug;17(8):524-32. doi: 10.1038/nrn.2016.57. Epub 2016 Jun 3.
3
[ACTINg out].[付诸行动]。
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4
Platelet serotonin in subtypes of schizophrenia and unipolar depression.
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Integrated theory to unify status among schizophrenia and manic depressive illness.整合理论以统一精神分裂症和躁郁症之间的状况。
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7
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9
[Differences in serotonin and dopamine metabolism in psychopathy and sluggish schizophrenia].
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Beyond the dopamine hypothesis of schizophrenia to three neural networks of psychosis: dopamine, serotonin, and glutamate.超越精神分裂症的多巴胺假说到三个精神病的神经网络：多巴胺、血清素和谷氨酸。
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本文引用的文献

1
The serotonin theory of depression: a systematic umbrella review of the evidence.抑郁的 5-羟色胺理论：证据的系统伞状评价。
Mol Psychiatry. 2023 Aug;28(8):3243-3256. doi: 10.1038/s41380-022-01661-0. Epub 2022 Jul 20.
2
Culturally sanctioned "scientific pluralism" opens the backdoor for the supernatural in Psychiatry.文化认可的“科学多元主义”为精神病学中的超自然现象打开了后门。
Acta Psychiatr Scand. 2022 Jan;145(1):109-110. doi: 10.1111/acps.13382. Epub 2021 Nov 10.
3
Should denialism of mental illness and its treatment be included among conspiracy theories?
对精神疾病及其治疗的否认是否应被纳入阴谋论之中？
Eur Arch Psychiatry Clin Neurosci. 2021 Jun;271(4):591-593. doi: 10.1007/s00406-021-01272-w.
4
Interpreting the Findings of a Meta-analysis of Psychosocial Interventions in Bipolar Disorder.解读双相情感障碍心理社会干预荟萃分析的结果
JAMA Psychiatry. 2021 Apr 1;78(4):447-448. doi: 10.1001/jamapsychiatry.2020.4412.
5
The effects of blinding on the outcomes of psychotherapy and pharmacotherapy for adult depression: A meta-analysis.盲法对成人抑郁症心理治疗和药物治疗结局的影响：一项荟萃分析。
Eur Psychiatry. 2015 Sep;30(6):685-93. doi: 10.1016/j.eurpsy.2015.06.005. Epub 2015 Jul 11.
6
Are antidepressants clinically useful? Conclusion of a decade of debate.抗抑郁药在临床上有用吗？十年辩论的结论。
World Psychiatry. 2014 Jun;13(2):201-2. doi: 10.1002/wps.20112.
7
No differences between drug naive and drug experienced unipolar depressed patients in terms of neurobiological testing: a cross sectional study.在神经生物学测试方面，药物初治和药物经验丰富的单相抑郁患者之间没有差异：一项横断面研究。
J Psychiatr Res. 2013 Dec;47(12):1984-90. doi: 10.1016/j.jpsychires.2013.09.004. Epub 2013 Sep 18.
8
No role for initial severity on the efficacy of antidepressants: results of a multi-meta-analysis.抗抑郁药疗效与初始严重程度无关：一项多荟萃分析的结果。
Ann Gen Psychiatry. 2013 Aug 13;12(1):26. doi: 10.1186/1744-859X-12-26.
9
Antipsychotic drugs versus placebo for relapse prevention in schizophrenia: a systematic review and meta-analysis.抗精神病药物与安慰剂治疗精神分裂症复发的比较：系统评价和荟萃分析。
Lancet. 2012 Jun 2;379(9831):2063-71. doi: 10.1016/S0140-6736(12)60239-6. Epub 2012 May 3.